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Background <p>Monitoring intravascular volume is crucial for predicting and preventing intradialytic hypotension (IDH). Stroke volume variation (SVV) is a highly sensitive indicator of changes in plasma volume.</p> Methods <p>The ClearSight system was used to continuously monitor SVV in nine hemodialysis (HD) patients with diabetes mellitus, six of whom experienced intradialytic hypotension (IDH) during HD sessions. This study aimed to investigate changes in SVV over time and the response of SVV to intravenous fluid bolus administration.</p> Results <p>SVV increased in all patients with IDH but was stable in patients without IDH. Two cases of IDH exhibited a slow increase in SVV and decrease in systolic blood pressure (SBP) following the initiation of HD sessions. In three cases of IDH with SVV elevation, a rapid decrease in SVV and an increase in SBP were observed soon after intravenous fluid loading. In patients with IDH who did not receive intravenous fluid replacement and were treated only with vasoconstrictors, the SVV did not decrease and remained elevated.</p> Conclusions <p>Continuous monitoring of the SVV during HD sessions using the ClearSight system may be useful for intravascular volume monitoring, providing invaluable insights into the pathophysiology of IDH and direct targeted therapeutic interventions.</p>

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The utility of stroke volume variation for intravascular volume monitoring during hemodialysis sessions: a case–control pilot study

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年7月1日

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  • Tatsunori Hamamoto,
  • Tetsu Miyamoto,
  • Towa Furuko,
  • Yutaro Sato,
  • Konatsu Ikeda,
  • Masamitsu Tanaka,
  • Kazuhisa Takahashi,
  • Norihito Sato,
  • Ikutaro Furuno,
  • Kazutoshi Nakazono,
  • Hiromichi Ueno,
  • Emi Hasegawa,
  • Masaharu Kataoka

摘要

Background

Monitoring intravascular volume is crucial for predicting and preventing intradialytic hypotension (IDH). Stroke volume variation (SVV) is a highly sensitive indicator of changes in plasma volume.

Methods

The ClearSight system was used to continuously monitor SVV in nine hemodialysis (HD) patients with diabetes mellitus, six of whom experienced intradialytic hypotension (IDH) during HD sessions. This study aimed to investigate changes in SVV over time and the response of SVV to intravenous fluid bolus administration.

Results

SVV increased in all patients with IDH but was stable in patients without IDH. Two cases of IDH exhibited a slow increase in SVV and decrease in systolic blood pressure (SBP) following the initiation of HD sessions. In three cases of IDH with SVV elevation, a rapid decrease in SVV and an increase in SBP were observed soon after intravenous fluid loading. In patients with IDH who did not receive intravenous fluid replacement and were treated only with vasoconstrictors, the SVV did not decrease and remained elevated.

Conclusions

Continuous monitoring of the SVV during HD sessions using the ClearSight system may be useful for intravascular volume monitoring, providing invaluable insights into the pathophysiology of IDH and direct targeted therapeutic interventions.