<p>This umbrella review evaluated the effects of Technology-Based Exercise (Tele-exercise) on balance and Quality of Life (QoL) in individuals with multiple sclerosis (MS). A comprehensive search across multiple databases identified meta-analyses and individual studies published up to June 3, 2025. Eligible studies included meta-analyses assessing tele-exercise interventions, while reviews with insufficient data were excluded. Methodological quality was assessed using the Measurement Tool to Assess Systematic Reviews 2 (AMSTAR-2) checklist. The pooled findings indicate that tele-exercise is not associated with meaningful improvements in balance among individuals with multiple sclerosis (SMD = 0.587, 95% CI: -0.533–1.706, <i>N</i> = 243 based on SMD). Likewise, tele-exercise shows minimal impact on quality of life (QOL) (SMD = 0.169, 95% CI: -0.025-0.362, <i>N</i> = 407 based on SMD). Although trends toward benefit were observed, findings remain inconclusive due to variability in protocols, methodological limitations, and low patient engagement. Overall, tele-exercise is feasible and may support patient-centered care, but current evidence does not confirm significant improvements in balance and QoL for people with MS. Standardized protocols, greater personalization, and higher-quality trials are needed to strengthen future clinical guidelines.</p>

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Effectiveness of technology-based exercise on motor function and quality of life in individuals with multiple sclerosis: an umbrella review

  • Mahboubeh Ghayour Najafabadi,
  • Ardalan Shariat,
  • Mahdi Hadi,
  • Kian Bagheri,
  • Hanieh Akbarimehr,
  • Laila Rahmah,
  • Farimah Mahinpour,
  • Nikki Maleki

摘要

This umbrella review evaluated the effects of Technology-Based Exercise (Tele-exercise) on balance and Quality of Life (QoL) in individuals with multiple sclerosis (MS). A comprehensive search across multiple databases identified meta-analyses and individual studies published up to June 3, 2025. Eligible studies included meta-analyses assessing tele-exercise interventions, while reviews with insufficient data were excluded. Methodological quality was assessed using the Measurement Tool to Assess Systematic Reviews 2 (AMSTAR-2) checklist. The pooled findings indicate that tele-exercise is not associated with meaningful improvements in balance among individuals with multiple sclerosis (SMD = 0.587, 95% CI: -0.533–1.706, N = 243 based on SMD). Likewise, tele-exercise shows minimal impact on quality of life (QOL) (SMD = 0.169, 95% CI: -0.025-0.362, N = 407 based on SMD). Although trends toward benefit were observed, findings remain inconclusive due to variability in protocols, methodological limitations, and low patient engagement. Overall, tele-exercise is feasible and may support patient-centered care, but current evidence does not confirm significant improvements in balance and QoL for people with MS. Standardized protocols, greater personalization, and higher-quality trials are needed to strengthen future clinical guidelines.