<p>This study explores sustainability and circular economic practices of small and medium-sized enterprises (SMEs) in Nigeria. The research investigates the experiences and challenges faced by SMEs as they seek to navigate the implementation of circular and sustainable practices. Drawing on an integrated theoretical framework, the study combines the sustainability, entrepreneurship and strategic orientation literature to evaluate the interrelationship between these concepts. Through the use of questionnaire surveys conducted with entrepreneurs in Lagos Nigeria, the research helps fill the gap in the literature on circular economy practices of SMEs and makes recommendations to policymakers for the effective development of policy initiatives that promote a responsive approach to the SME sector. The research also proposes several strategies and policy initiatives to assist SMEs in developing requisite skills and knowledge to enable them to confidently implement environmental sustainability and circularity practices.</p>