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Background <p>Stroke has devastating consequences for survivors. Hypertension is the most important modifiable risk factor, and its management largely takes place in primary care. However, most stroke-based research does not occur in this setting. Ongoing hypertension and a risk of further stroke are a major concern for both patients and their general practitioners. We aim to assess whether it is feasible to assess prognosis in persons, with a previous stroke or transient ischemic attack (TIA), in general practice, and whether a well-powered observational study is possible.</p> Methods <p>We performed a search of the electronic health record of individuals previously identified as having had a stroke or TIA, to assess prognosis over 3&#xa0;years. Feasibility was assessed by meeting five criteria: (1) all general practices approached participated, (2) greater than 90% of patient records were accessible, (3) all study outcomes were available to review, (4) that collection data was less than 15&#xa0;min per patient, and (5) a power calculation for a planned observational study could take place.</p> Results <p>All six general practices approached participated freely, and 193/196 patients’ files were reidentified (98.5%). Twenty-eight cardiovascular events were recorded—most commonly a repeat TIA or ischemic stroke. Data collection took on average 5.5&#xa0;min per file, and a power calculation for a planned observational study was completed.</p> Conclusion <p>This study demonstrates that the proposed methodology for a full cohort study within general practice of patients post-stroke/TIA is both acceptable to practices and feasible. An adequately powered, “time-to-event” study is possible.</p>

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The feasibility of assessing prognosis over 3 years in persons with a previous stroke/transient ischemic attack in general practice

  • 期刊论文

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  • 发表日期：

    2025年1月25日

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  • Eimear Ryan,
  • Harmeet Gill,
  • Róisín Doogue,
  • David McCann,
  • Andrew W. Murphy,
  • Peter Hayes

摘要

Background

Stroke has devastating consequences for survivors. Hypertension is the most important modifiable risk factor, and its management largely takes place in primary care. However, most stroke-based research does not occur in this setting. Ongoing hypertension and a risk of further stroke are a major concern for both patients and their general practitioners. We aim to assess whether it is feasible to assess prognosis in persons, with a previous stroke or transient ischemic attack (TIA), in general practice, and whether a well-powered observational study is possible.

Methods

We performed a search of the electronic health record of individuals previously identified as having had a stroke or TIA, to assess prognosis over 3 years. Feasibility was assessed by meeting five criteria: (1) all general practices approached participated, (2) greater than 90% of patient records were accessible, (3) all study outcomes were available to review, (4) that collection data was less than 15 min per patient, and (5) a power calculation for a planned observational study could take place.

Results

All six general practices approached participated freely, and 193/196 patients’ files were reidentified (98.5%). Twenty-eight cardiovascular events were recorded—most commonly a repeat TIA or ischemic stroke. Data collection took on average 5.5 min per file, and a power calculation for a planned observational study was completed.

Conclusion

This study demonstrates that the proposed methodology for a full cohort study within general practice of patients post-stroke/TIA is both acceptable to practices and feasible. An adequately powered, “time-to-event” study is possible.