Background <p>Despite Ethiopia’s agricultural potential and policy efforts, food insecurity and malnutrition remain major challenges, particularly among children. The Ethiopian government has launched programs to improve food security and nutrition in the country. However, the effectiveness of these initiatives in addressing child malnutrition and food insecurity has not been comprehensively reviewed yet.</p> Methods <p>A systematic review following the PRISMA guidelines was conducted to evaluate the impact of food and nutrition programs on child nutrition and household food security in Ethiopia. A comprehensive search of PubMed, Scopus, Web of Science, and Google Scholar identified relevant studies published between 2015 and March 2025. Fourteen studies focusing on various program types in the country were included.</p> Results <p>Studies have reported inconsistent results regarding the effectiveness of food and nutrition programs in improving child anthropometry and household food security outcomes. Combined programs positively affected child nutrition, including reduced stunting and wasting, whereas single programs had limited impact. Program effectiveness varies by geography, seasonality, and socioeconomic conditions. Multicomponent programs, women’s empowerment, and community engagement were critical to effectiveness.</p> Conclusion <p>This review highlights the importance of multi-component interventions in enhancing child nutrition and food security. Policymakers should design context-specific interventions that address geographical, seasonal, and socioeconomic variation. Future programs should focus on long-term sustainability, maternal and child health education, improved access to nutritious foods, strengthening social safety nets, and integrating programs. Enhanced community engagement and further investigation into the long-term effects of these programs are crucial for their efficacy and resilience against climate change and economic challenges.</p>