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<p>Traumatic brain injury (TBI) is still considered a major cause of morbidity and mortality worldwide, and its prevalence is increasing daily. TBI patients are facing difficult diagnostic, management, and rehabilitative challenges. This review article represents the most relevant recent findings in all areas of TBI concerning pathophysiology, diagnostics, therapeutics, rehabilitation approaches and neuroplasticity. In recent years, the diagnosis of TBI has improved more often due to advancements in neuroimaging, biomarkers, and artificial intelligence. Pharmacological treatments, stem cell therapy, and neuroprotective strategies are also associated with a wide range of therapeutic innovations that could open new fields of acute management. Consequently, practice has also changed, and cross professional treatments have been adopted with the aid of the latest technology for acute TBI recovery. TBI management faces multiple challenges in special populations, such as pediatric patients, elderly people, and soldiers. Personalized medicine, big data analytics, and global collaboration are emphasized as future research directions. This detailed study should serve to remind researchers and clinicians alike of the ongoing need for innovation to deliver better care pathways appropriate for TBI patients.</p>

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Revolutionizing cross professional collaboration outcomes in TBI: emerging trends in diagnostics, personalized medicine, technological innovations and neurorehabilitation

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年9月2日

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  • Mubin Mustafa Kiyani,
  • Shahid Bashir,
  • Benish Shahzadi,
  • Hamid Khan,
  • Maisra Azhar Butt,
  • Syed Ali Hussain,
  • Turki Abualait

摘要

Traumatic brain injury (TBI) is still considered a major cause of morbidity and mortality worldwide, and its prevalence is increasing daily. TBI patients are facing difficult diagnostic, management, and rehabilitative challenges. This review article represents the most relevant recent findings in all areas of TBI concerning pathophysiology, diagnostics, therapeutics, rehabilitation approaches and neuroplasticity. In recent years, the diagnosis of TBI has improved more often due to advancements in neuroimaging, biomarkers, and artificial intelligence. Pharmacological treatments, stem cell therapy, and neuroprotective strategies are also associated with a wide range of therapeutic innovations that could open new fields of acute management. Consequently, practice has also changed, and cross professional treatments have been adopted with the aid of the latest technology for acute TBI recovery. TBI management faces multiple challenges in special populations, such as pediatric patients, elderly people, and soldiers. Personalized medicine, big data analytics, and global collaboration are emphasized as future research directions. This detailed study should serve to remind researchers and clinicians alike of the ongoing need for innovation to deliver better care pathways appropriate for TBI patients.