Background <p>This study examined the associations between posttraumatic stress symptoms (PTSS), anxiety, depression, and negative interpretation bias in breast cancer patients, with a specific focus on the potential mediating role of negative interpretation bias.</p> Methods <p>Eighty breast cancer patients completed a cross-sectional assessment including the Impact of Event Scale (IES), the Hospital Anxiety and Depression Scale (HADS), and an ambiguous emotional face recognition task. Participants were categorized into PTSS and non-PTSS groups based on IES scores. Data were analyzed using descriptive statistics, independent-samples <i>t</i>-tests, ANOVA, and mediation analyses (PROCESS Model 4, 5,000 bootstraps, 95% CI).</p> Results <p>Patients with PTSS reported significantly higher levels of anxiety and depression, and demonstrated a stronger tendency to interpret ambiguous emotional expressions in a negative manner. Negative interpretation bias partially mediated the association between PTSS and emotional distress.</p> Conclusions <p>Breast cancer patients with PTSS tend to experience heightened emotional distress, which may be partly accounted for by negative interpretation bias. Additional psychological and physiological mechanisms may also contribute.</p>

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The effects of posttraumatic stress symptoms on anxiety and depression in patients with breast cancer: mediating role of negative interpretation bias

  • Miaomiao Wang,
  • Bingxue Han,
  • Yuxi Liu,
  • Shuai Teng,
  • Liping Jia,
  • Guohua Lu

摘要

Background

This study examined the associations between posttraumatic stress symptoms (PTSS), anxiety, depression, and negative interpretation bias in breast cancer patients, with a specific focus on the potential mediating role of negative interpretation bias.

Methods

Eighty breast cancer patients completed a cross-sectional assessment including the Impact of Event Scale (IES), the Hospital Anxiety and Depression Scale (HADS), and an ambiguous emotional face recognition task. Participants were categorized into PTSS and non-PTSS groups based on IES scores. Data were analyzed using descriptive statistics, independent-samples t-tests, ANOVA, and mediation analyses (PROCESS Model 4, 5,000 bootstraps, 95% CI).

Results

Patients with PTSS reported significantly higher levels of anxiety and depression, and demonstrated a stronger tendency to interpret ambiguous emotional expressions in a negative manner. Negative interpretation bias partially mediated the association between PTSS and emotional distress.

Conclusions

Breast cancer patients with PTSS tend to experience heightened emotional distress, which may be partly accounted for by negative interpretation bias. Additional psychological and physiological mechanisms may also contribute.