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<p>Non-obstructive myocardial stunning is characterized by transient myocardial contractile dysfunction despite preserved coronary perfusion. Although increasingly recognized, it remains a diagnostic and therapeutic challenge in cardiology. This review synthesizes current insights into reversible cardiomyopathies, explores the potential of antimetabolic and anti-ischemic agents in their management, and highlights emerging therapeutic avenues. Greater understanding of these mechanisms may improve patient outcomes in this underexplored area.</p>

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A review on fueling recovery: the role of metabolic modulation in non-obstructive myocardial stunning

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年12月5日

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  • Uğur Özkan,
  • Kenan Yalta,
  • Muhammet Gürdoğan,
  • Nicholas G. Kounis,
  • Servet Altay

摘要

Non-obstructive myocardial stunning is characterized by transient myocardial contractile dysfunction despite preserved coronary perfusion. Although increasingly recognized, it remains a diagnostic and therapeutic challenge in cardiology. This review synthesizes current insights into reversible cardiomyopathies, explores the potential of antimetabolic and anti-ischemic agents in their management, and highlights emerging therapeutic avenues. Greater understanding of these mechanisms may improve patient outcomes in this underexplored area.