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Aim <p>This randomized controlled trial aimed to assess the efficacy of a combined Nd:YAG&#xa0;laser and bioactive glass (BAG) for dentin hypersensitivity following scaling and root planning (SRP). The study compared various desensitization protocols and evaluated the time-dependent effects of immediate desensitization therapy post-SRP.</p> Methods <p>80 patients with chronic periodontitis (200 sensitive teeth) were randomly assigned to five groups: group A (BAG), group B (Nd:YAG laser), group C (Nd:YAG laser + BAG), group D (BAG + Nd:YAG laser), and group E (control). Hypersensitivity was assessed via air-blast stimulation and measured on a Visual Analogue Scale (VAS) at baseline (T0), immediately after intervention (T1), and at 1-, 4-, and 8-week (T2–T4) post-treatment. Between-group comparisons of baseline characteristics and post-treatment measurements were analyzed with one-way ANOVA. Longitudinal comparisons across timepoints were evaluated using repeated-measures ANOVA. Categorical variables were compared by chi-square test.</p> Results <p>No significant differences in demographic characteristics or baseline VAS scores were observed across the groups before treatment (<i>P</i> &gt; 0.05). All interventional groups (A–D) showed significant and sustained reductions in VAS scores relative to both baseline and control (all&#xa0;<i>P</i> &lt; 0.001), with group D achieving the greatest improvement at T4 (2.00 ± 0.68,&#xa0;<i>P</i> &lt; 0.05 vs. group C). Effectiveness rates were also significantly higher in groups A–D than in group E (all&#xa0;<i>P</i> &lt; 0.001). Combination therapies (C and D) proved superior to monotherapies (A and B), with group D maintaining the highest effectiveness rate through T4 (92.5%). A gradual decline in effectiveness was observed over time, being least pronounced in group D.</p> Conclusions <p>The combined application of BAG and Nd:YAG&#xa0;laser therapy demonstrated a significant reduction in dentin hypersensitivity post-SRP, exhibiting superior and sustained efficacy compared to monotherapies. Furthermore, the sequential treatment involving BAG applied prior to Nd:YAG&#xa0;laser irradiation showed the most pronounced therapeutic effect in symptom alleviation.</p>

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Clinical outcome of Nd:YAG laser and bioactive glass combined use for dentin hypersensitivity after scaling and root planning: a short-term comparative study

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年10月27日

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  • Kaixuan Yan,
  • Wei Si,
  • Jingxin Guo,
  • Jing Liu,
  • Yu Zheng,
  • Xiaowei Hou,
  • Shifeng Fan

摘要

Aim

This randomized controlled trial aimed to assess the efficacy of a combined Nd:YAG laser and bioactive glass (BAG) for dentin hypersensitivity following scaling and root planning (SRP). The study compared various desensitization protocols and evaluated the time-dependent effects of immediate desensitization therapy post-SRP.

Methods

80 patients with chronic periodontitis (200 sensitive teeth) were randomly assigned to five groups: group A (BAG), group B (Nd:YAG laser), group C (Nd:YAG laser + BAG), group D (BAG + Nd:YAG laser), and group E (control). Hypersensitivity was assessed via air-blast stimulation and measured on a Visual Analogue Scale (VAS) at baseline (T0), immediately after intervention (T1), and at 1-, 4-, and 8-week (T2–T4) post-treatment. Between-group comparisons of baseline characteristics and post-treatment measurements were analyzed with one-way ANOVA. Longitudinal comparisons across timepoints were evaluated using repeated-measures ANOVA. Categorical variables were compared by chi-square test.

Results

No significant differences in demographic characteristics or baseline VAS scores were observed across the groups before treatment (P > 0.05). All interventional groups (A–D) showed significant and sustained reductions in VAS scores relative to both baseline and control (all P < 0.001), with group D achieving the greatest improvement at T4 (2.00 ± 0.68, P < 0.05 vs. group C). Effectiveness rates were also significantly higher in groups A–D than in group E (all P < 0.001). Combination therapies (C and D) proved superior to monotherapies (A and B), with group D maintaining the highest effectiveness rate through T4 (92.5%). A gradual decline in effectiveness was observed over time, being least pronounced in group D.

Conclusions

The combined application of BAG and Nd:YAG laser therapy demonstrated a significant reduction in dentin hypersensitivity post-SRP, exhibiting superior and sustained efficacy compared to monotherapies. Furthermore, the sequential treatment involving BAG applied prior to Nd:YAG laser irradiation showed the most pronounced therapeutic effect in symptom alleviation.