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Objective <p>This study aimed to investigate the effects of a continuous comprehensive nursing (CCN) system compared to routine care on postoperative hemoglobin (Hb) levels and quality of life (QoL) in patients undergoing coronary artery bypass&#xa0;grafting&#xa0;(CABG).</p> Methods <p>This randomized controlled trial (RCT) enrolled 120 patients undergoing CABG. Patients were allocated using computer-generated random numbers (1:1) to either the intervention group (<i>n</i> = 60), receiving a CCN plan, or the control group (<i>n</i> = 60), receiving standard postoperative care. The CCN intervention provided a patient-centered approach encompassing preoperative education, psychological support, continuous postoperative monitoring, personalized care plans, rehabilitation guidance, and structured follow-up extending for three months beyond discharge.</p> Results <p>Although baseline differences in BMI and Hb were noted, both groups were otherwise comparable. While Hb levels initially declined in both groups, by day 7 post-surgery, the CCN group demonstrated significantly higher Hb levels compared to the control group (12.28 ± 0.47&#xa0;g/L vs. 9.16 ± 0.41&#xa0;g/L; <i>P</i> &lt; 0.001). The intervention group also showed significantly improved red blood cell morphology (lower MCV, <i>P</i> &lt; 0.001; lower RDW, <i>P</i> &lt; 0.001; higher HCT, <i>P</i> &lt; 0.001), changes in IL-2 and IL-6 levels suggesting an immune response difference (higher IL-2, <i>P</i> &lt; 0.001; lower IL-6, <i>P</i> &lt; 0.001), superior QoL scores across all WHOQOL domains (psychological, social, environmental, physical; all <i>P</i> &lt; 0.001), reduced depressive (CES-D, <i>P</i> &lt; 0.001) and anxiety symptoms (SAS, <i>P</i> &lt; 0.001), and significantly higher patient satisfaction (<i>P</i> &lt; 0.001).</p> Conclusion <p>Implementing a continuous comprehensive nursing system after CABG significantly benefits postoperative recovery, leading to improved hemoglobin levels, favorable red blood cell indices, measurable changes in immune markers, enhanced quality of life, improved mental health outcomes, and greater patient satisfaction compared to routine care. These findings suggest CCN is a promising strategy to optimize post-CABG patient outcomes.</p>

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Evaluating the efficacy of a continuous comprehensive nursing system on postoperative hemoglobin levels and quality of life in coronary artery bypass surgery: a randomized controlled trial

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年11月26日

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  • Pujuan Liu,
  • Beibei Xing,
  • Shang Wang,
  • Huili Liu,
  • Jing Wang,
  • Man Zhang,
  • Hong Shen

摘要

Objective

This study aimed to investigate the effects of a continuous comprehensive nursing (CCN) system compared to routine care on postoperative hemoglobin (Hb) levels and quality of life (QoL) in patients undergoing coronary artery bypass grafting (CABG).

Methods

This randomized controlled trial (RCT) enrolled 120 patients undergoing CABG. Patients were allocated using computer-generated random numbers (1:1) to either the intervention group (n = 60), receiving a CCN plan, or the control group (n = 60), receiving standard postoperative care. The CCN intervention provided a patient-centered approach encompassing preoperative education, psychological support, continuous postoperative monitoring, personalized care plans, rehabilitation guidance, and structured follow-up extending for three months beyond discharge.

Results

Although baseline differences in BMI and Hb were noted, both groups were otherwise comparable. While Hb levels initially declined in both groups, by day 7 post-surgery, the CCN group demonstrated significantly higher Hb levels compared to the control group (12.28 ± 0.47 g/L vs. 9.16 ± 0.41 g/L; P < 0.001). The intervention group also showed significantly improved red blood cell morphology (lower MCV, P < 0.001; lower RDW, P < 0.001; higher HCT, P < 0.001), changes in IL-2 and IL-6 levels suggesting an immune response difference (higher IL-2, P < 0.001; lower IL-6, P < 0.001), superior QoL scores across all WHOQOL domains (psychological, social, environmental, physical; all P < 0.001), reduced depressive (CES-D, P < 0.001) and anxiety symptoms (SAS, P < 0.001), and significantly higher patient satisfaction (P < 0.001).

Conclusion

Implementing a continuous comprehensive nursing system after CABG significantly benefits postoperative recovery, leading to improved hemoglobin levels, favorable red blood cell indices, measurable changes in immune markers, enhanced quality of life, improved mental health outcomes, and greater patient satisfaction compared to routine care. These findings suggest CCN is a promising strategy to optimize post-CABG patient outcomes.