Scholarlink

<p>This paper proposes an interaction model for vaccination and infectious disease transmission, structured as a hierarchical three-layered network encompassing individuals, households, and communities, to investigate how vaccine priorities influence vaccination uptake. Longitudinal data on influenza-like illness cases is used to estimate the model parameters. Analyzing household and community structures reveals that a broader community radius and prioritizing community payoffs increase individuals’ sensitivity to information, enabling them to respond swiftly to changes in vaccination costs. Two vaccination strategies are compared: the Infection Prevention Effectiveness (IPE) strategy and the Severe Illness Prevention Effectiveness (SIPE) strategy. The IPE strategy achieves higher vaccination rates, better reducing infections and severe cases than the SIPE strategy. While enhancing vaccine effectiveness significantly promotes vaccination under the IPE approach, it has a negligible effect on uptake under SIPE. Conversely, reducing vaccine costs emerges as a much more powerful lever for boosting vaccination rates within the SIPE framework. When societal goals to reduce infections diverge from individuals’ focus on preventing severe illness, vaccination rates fall well below the optimal level, resulting in inadequate control of both infections and severe cases. These results highlight the importance of tailoring prevention and control measures to align with both societal and individual goals.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Preventing infection vs. severe illness in a three-layered network: how vaccine priorities shape vaccination uptake

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年9月30日

查看全文
  • Weiyang Zhang,
  • Xingyu Xiang,
  • Shu Wang,
  • Xiaodan Sun

摘要

This paper proposes an interaction model for vaccination and infectious disease transmission, structured as a hierarchical three-layered network encompassing individuals, households, and communities, to investigate how vaccine priorities influence vaccination uptake. Longitudinal data on influenza-like illness cases is used to estimate the model parameters. Analyzing household and community structures reveals that a broader community radius and prioritizing community payoffs increase individuals’ sensitivity to information, enabling them to respond swiftly to changes in vaccination costs. Two vaccination strategies are compared: the Infection Prevention Effectiveness (IPE) strategy and the Severe Illness Prevention Effectiveness (SIPE) strategy. The IPE strategy achieves higher vaccination rates, better reducing infections and severe cases than the SIPE strategy. While enhancing vaccine effectiveness significantly promotes vaccination under the IPE approach, it has a negligible effect on uptake under SIPE. Conversely, reducing vaccine costs emerges as a much more powerful lever for boosting vaccination rates within the SIPE framework. When societal goals to reduce infections diverge from individuals’ focus on preventing severe illness, vaccination rates fall well below the optimal level, resulting in inadequate control of both infections and severe cases. These results highlight the importance of tailoring prevention and control measures to align with both societal and individual goals.