Scholarlink

Background <p>Isotopic renography is pivotal for assessing upper urinary tract obstruction and provides renal functional parameters. New 3D-CZT cameras offer enhanced sensitivity and innovative full SPECT protocols that need to be validated on phantoms. Current renal phantoms are often complex and suitable for 2D imaging. Using a new printed 3D renal phantom, we compared planar and full SPECT dynamic imaging. Methods: A 3D-printed renal phantom mimicking pediatric/adult kidneys was designed. Each kidney subunit, connected to a bladder-bag, was programmably infused with 7.5 MBq of [<sup>99m</sup>Tc]-Pertechnetate to simulate normal nephrograms. An asymmetry of renal activity was simulated using different activity ratios. Each acquisition was conducted on both conventional NaI(Tl) and 3D-CZT cameras. Results: The 3D printed phantom enabled the acquisition of consistent and reproducible nephrograms. T<sub>max</sub>, T<sub>1/2</sub>, and A<sub>20 − min/max</sub> ratios showed no statistically significant differences between planar and SPECT. Simulated asymmetric renal function demonstrated a strong linear correlation between activity and AUC with <i>r</i> = 0.9455 and 0.9471 (<i>p</i> &lt; 0.0001), respectively for conventional and 3D cameras. Conclusion: This innovative 3D phantom allowed the acquisition of reproducible nephrograms with parameters comparable to those of clinical examinations. At low activity, 3D-CZT camera acquisitions provided equivalent values to conventional cameras, supporting their use for qualitative imaging and follow-up.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Renal dynamic scintigraphy using 3D-ring CZT cameras: comparison with NaI(Tl)

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年12月10日

查看全文
  • Gilles Metrard,
  • Gilles Le Rouzic,
  • Benoit Chapelle,
  • Diane Darsin-Bettinger,
  • Manon Dekeyser,
  • Matthieu Bailly

摘要

Background

Isotopic renography is pivotal for assessing upper urinary tract obstruction and provides renal functional parameters. New 3D-CZT cameras offer enhanced sensitivity and innovative full SPECT protocols that need to be validated on phantoms. Current renal phantoms are often complex and suitable for 2D imaging. Using a new printed 3D renal phantom, we compared planar and full SPECT dynamic imaging. Methods: A 3D-printed renal phantom mimicking pediatric/adult kidneys was designed. Each kidney subunit, connected to a bladder-bag, was programmably infused with 7.5 MBq of [99mTc]-Pertechnetate to simulate normal nephrograms. An asymmetry of renal activity was simulated using different activity ratios. Each acquisition was conducted on both conventional NaI(Tl) and 3D-CZT cameras. Results: The 3D printed phantom enabled the acquisition of consistent and reproducible nephrograms. Tmax, T1/2, and A20 − min/max ratios showed no statistically significant differences between planar and SPECT. Simulated asymmetric renal function demonstrated a strong linear correlation between activity and AUC with r = 0.9455 and 0.9471 (p < 0.0001), respectively for conventional and 3D cameras. Conclusion: This innovative 3D phantom allowed the acquisition of reproducible nephrograms with parameters comparable to those of clinical examinations. At low activity, 3D-CZT camera acquisitions provided equivalent values to conventional cameras, supporting their use for qualitative imaging and follow-up.