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Background <p>Oncocytic lipoadenoma is an extremely rare benign tumor of the salivary glands, with fewer than 50 cases reported in the literature. Most cases occur in the parotid gland, with atypical locations presenting diagnostic challenges.</p> Case presentation <p>We report a case of a 53-year-old Iranian man presenting with a large parapharyngeal mass originating from the deep lobe of the parotid gland. The patient had a 7-year history of a slowly enlarging, painless swelling, with recent onset of dysphagia, dyspnea, and choking sensation. MRI revealed a giant 10 × 7.4 × 3.5&#xa0;cm mass in the left deep parotid extending to&#xa0;the parapharyngeal space, causing severe airway compression.</p> Conclusion <p>Our case highlights the importance of considering oncocytic lipoadenoma in the differential diagnosis of parapharyngeal masses and emphasizes the need for thorough histological examination. It contributes to the limited literature on this rare tumor and illustrates the potential for atypical presentations and growth patterns.</p>

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Oncocytic lipoadenoma of the parotid presenting as an unusual neck mass: a case report

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  • 发表日期：

    2026年7月19日

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  • Somayeh Sheidaei,
  • Mahdi Naeimaei Aali,
  • Saman Rezaei

摘要

Background

Oncocytic lipoadenoma is an extremely rare benign tumor of the salivary glands, with fewer than 50 cases reported in the literature. Most cases occur in the parotid gland, with atypical locations presenting diagnostic challenges.

Case presentation

We report a case of a 53-year-old Iranian man presenting with a large parapharyngeal mass originating from the deep lobe of the parotid gland. The patient had a 7-year history of a slowly enlarging, painless swelling, with recent onset of dysphagia, dyspnea, and choking sensation. MRI revealed a giant 10 × 7.4 × 3.5 cm mass in the left deep parotid extending to the parapharyngeal space, causing severe airway compression.

Conclusion

Our case highlights the importance of considering oncocytic lipoadenoma in the differential diagnosis of parapharyngeal masses and emphasizes the need for thorough histological examination. It contributes to the limited literature on this rare tumor and illustrates the potential for atypical presentations and growth patterns.