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Background <p>Endosalpingiosis is a rare benign condition characterized by the ectopic presence of ciliated tub epithelium outside the fallopian tubes, often found in the ovaries, uterus, and other pelvic structures.</p> Case presentation <p>This case report presents a 21-year-old Iranian woman who presented to the emergency department with severe right lower quadrant abdominal pain, nausea, and a feeling of fever. Despite normal imaging results, histopathological examination following laparoscopic appendicectomy revealed appendiceal endosalpingiosis. Following appendicectomy, all signs and symptoms were relieved. This rare phenomenon highlights another rare but important differential diagnosis of appendicitis.</p> Conclusions <p>Given the limited number of reported cases, further investigation is necessary to understand the mechanism and clinical significance of endosalpingiosis. Due to its potential association with gynecological pathologies, we recommend systematic gynecological evaluation in these patients.</p>

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Appendiceal endosalpingiosis: a case report and review of the literature

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年4月30日

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  • Ahmad Madankan,
  • Kimia Jazi,
  • Yasamin Bigdeli,
  • Mahsa Jafari Harandi,
  • Ali Zare-Mirzaei

摘要

Background

Endosalpingiosis is a rare benign condition characterized by the ectopic presence of ciliated tub epithelium outside the fallopian tubes, often found in the ovaries, uterus, and other pelvic structures.

Case presentation

This case report presents a 21-year-old Iranian woman who presented to the emergency department with severe right lower quadrant abdominal pain, nausea, and a feeling of fever. Despite normal imaging results, histopathological examination following laparoscopic appendicectomy revealed appendiceal endosalpingiosis. Following appendicectomy, all signs and symptoms were relieved. This rare phenomenon highlights another rare but important differential diagnosis of appendicitis.

Conclusions

Given the limited number of reported cases, further investigation is necessary to understand the mechanism and clinical significance of endosalpingiosis. Due to its potential association with gynecological pathologies, we recommend systematic gynecological evaluation in these patients.