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Background <p>The association between oral contraceptive pills and cardiovascular events, including myocardial infarction, has been a subject of debate in the medical literature. While previous studies have suggested a potential link between estrogen-containing contraceptives and an increased risk of thrombotic events, the absolute risk remains low, particularly in young, healthy women without underlying cardiovascular risk factors.</p> Case presentation <p>We report a rare case of a 32-year-old healthy Lebanese female patient with no significant past medical history or cardiovascular risk factors who developed acute coronary syndrome due to coronary artery thrombosis 8 months after initiating oral contraceptive pills (Yasmin tablets; 3.0 mg drospirenone and 0.030 mg ethinyl estradiol).</p> Conclusion <p>This case highlights the need for heightened vigilance and awareness of the potential arterial thrombosis risk associated with oral contraceptive pill use, especially in young women with no other cardiovascular risk factors.</p>

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Acute ST elevation myocardial infarction in a young female patient without cardiovascular risk factors—Massive left main coronary artery thrombosis induced by oral contraceptive pills: a case report

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年11月21日

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  • Samar Younes,
  • Rasha Jbara,
  • Mohamad Rahal,
  • Marwa Seblani,
  • Reina Zoghbi,
  • Jawad Krayem,
  • Yumna Skhaita,
  • Hamze Nasser

摘要

Background

The association between oral contraceptive pills and cardiovascular events, including myocardial infarction, has been a subject of debate in the medical literature. While previous studies have suggested a potential link between estrogen-containing contraceptives and an increased risk of thrombotic events, the absolute risk remains low, particularly in young, healthy women without underlying cardiovascular risk factors.

Case presentation

We report a rare case of a 32-year-old healthy Lebanese female patient with no significant past medical history or cardiovascular risk factors who developed acute coronary syndrome due to coronary artery thrombosis 8 months after initiating oral contraceptive pills (Yasmin tablets; 3.0 mg drospirenone and 0.030 mg ethinyl estradiol).

Conclusion

This case highlights the need for heightened vigilance and awareness of the potential arterial thrombosis risk associated with oral contraceptive pill use, especially in young women with no other cardiovascular risk factors.