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Background <p>Infective endocarditis occasionally presents with antineutrophil cytoplasmic antibody positivity, leading to diagnostic challenges and confusion, as it can be mislabeled antineutrophil-cytoplasmic-antibody-associated vasculitis. Distinguishing between these two factors is crucial for appropriate management.</p> Case presentation <p>In this case report, we describe a 77-year-old White non-Hispanic male patient who initially presented with features suggestive of antineutrophil-cytoplasmic-antibody-associated vasculitis but was ultimately diagnosed with infective endocarditis.</p> Conclusion <p>Our findings emphasize the need to rule out infective endocarditis in patients with suspected antineutrophil-cytoplasmic-antibody-associated vasculitis, as it can be the same, and management relies on different lines of therapy. Immunosuppression therapy can lead to devastating effects in patients with infective endocarditis.</p>

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Infective endocarditis mimicking antineutrophil-cytoplasmic-antibody-associated vasculitis with glomerulonephritis: a case report

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年8月4日

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  • Ahmad Matarneh,
  • Sundus Sardar,
  • Abdelrauof Akkari,
  • Omar Salameh,
  • Naman Trivedi,
  • Muhammad Abdulbasit,
  • Navin Verma,
  • Ronald Miller,
  • Nasrollah Ghahramani

摘要

Background

Infective endocarditis occasionally presents with antineutrophil cytoplasmic antibody positivity, leading to diagnostic challenges and confusion, as it can be mislabeled antineutrophil-cytoplasmic-antibody-associated vasculitis. Distinguishing between these two factors is crucial for appropriate management.

Case presentation

In this case report, we describe a 77-year-old White non-Hispanic male patient who initially presented with features suggestive of antineutrophil-cytoplasmic-antibody-associated vasculitis but was ultimately diagnosed with infective endocarditis.

Conclusion

Our findings emphasize the need to rule out infective endocarditis in patients with suspected antineutrophil-cytoplasmic-antibody-associated vasculitis, as it can be the same, and management relies on different lines of therapy. Immunosuppression therapy can lead to devastating effects in patients with infective endocarditis.