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Background <p>CO<sub>2</sub> embolism has been documented in a range of laparoscopic procedures, and cerebral CO<sub>2</sub> embolism is an extremely rare but lethal incidence of CO<sub>2</sub> embolism, which may ultimately result in coma, stroke, disability, and mortality.</p> Case presentation <p>This paper presents an uncommon case of cerebral CO<sub>2</sub> embolism that occurred during laparoscopic surgery, along with a thorough examination of existing literature. The patient (56-year-old Chinese female) experienced a loss of consciousness, generalized tonic–clonic seizures, and neurological impairments after undergoing a laparoscopic partial adrenalectomy. Multiple low-density lesions were detected by brain magnetic resonance imaging. The patient exhibited improvement and gradual recovery after undergoing therapies such as continuous hyperbaric oxygen therapy, hypothermic brain protection, hormone therapy, and anticoagulation.</p> Conclusion <p>We emphasize that cerebral CO<sub>2</sub> embolism is a significant complication that must be given great importance in laparoscopic surgery. The comprehension of cerebral CO<sub>2</sub> embolism, and effective communication between surgeons and anesthesiologists, play a crucial role in its diagnosis and avoiding inadequate treatment.</p>

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Occurrence of cerebral CO2 embolism during laparoscopic adrenalectomy: a case report and review of the literature

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年7月1日

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  • Miaomiao Xu,
  • Jiejie Zhou,
  • Xuemei Cheng,
  • Yunfei Han,
  • Kangli Hui

摘要

Background

CO2 embolism has been documented in a range of laparoscopic procedures, and cerebral CO2 embolism is an extremely rare but lethal incidence of CO2 embolism, which may ultimately result in coma, stroke, disability, and mortality.

Case presentation

This paper presents an uncommon case of cerebral CO2 embolism that occurred during laparoscopic surgery, along with a thorough examination of existing literature. The patient (56-year-old Chinese female) experienced a loss of consciousness, generalized tonic–clonic seizures, and neurological impairments after undergoing a laparoscopic partial adrenalectomy. Multiple low-density lesions were detected by brain magnetic resonance imaging. The patient exhibited improvement and gradual recovery after undergoing therapies such as continuous hyperbaric oxygen therapy, hypothermic brain protection, hormone therapy, and anticoagulation.

Conclusion

We emphasize that cerebral CO2 embolism is a significant complication that must be given great importance in laparoscopic surgery. The comprehension of cerebral CO2 embolism, and effective communication between surgeons and anesthesiologists, play a crucial role in its diagnosis and avoiding inadequate treatment.