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Background <p><i>Candida auris</i> ventriculitis is a rare but serious condition associated with high mortality rates. The available literature on its management is limited, and there are few documented successful treatment strategies or care plans.</p> Case presentation <p>We report the case of a 34-year-old male patient from South Asia with <i>Candida auris</i> infection of an external ventricular shunt. The patient was initially treated with a combination of injectable amphotericin B liposomal and caspofungin for 21&#xa0;days. This was followed by a 15-day course of injectable amphotericin liposomal and voriconazole. Subsequently, voriconazole monotherapy was administered orally for an additional 11&#xa0;days. Notably, all antifungals used were determined to be sensitive on the basis of cerebrospinal fluid culture and sensitivity results. Source control was achieved after 20&#xa0;days of initiating therapy, leading to the permanent removal of the shunt.</p> Conclusion <p><i>Candida auris</i> ventriculitis can be effectively managed with systemic antifungal therapy and appropriate source control measures.</p>

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Successful management of Candida auris external ventricular shunt infection: a case report

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年8月5日

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  • Ahmad Elhaj,
  • Duaa Jawhar,
  • Nawal Elfaki

摘要

Background

Candida auris ventriculitis is a rare but serious condition associated with high mortality rates. The available literature on its management is limited, and there are few documented successful treatment strategies or care plans.

Case presentation

We report the case of a 34-year-old male patient from South Asia with Candida auris infection of an external ventricular shunt. The patient was initially treated with a combination of injectable amphotericin B liposomal and caspofungin for 21 days. This was followed by a 15-day course of injectable amphotericin liposomal and voriconazole. Subsequently, voriconazole monotherapy was administered orally for an additional 11 days. Notably, all antifungals used were determined to be sensitive on the basis of cerebrospinal fluid culture and sensitivity results. Source control was achieved after 20 days of initiating therapy, leading to the permanent removal of the shunt.

Conclusion

Candida auris ventriculitis can be effectively managed with systemic antifungal therapy and appropriate source control measures.