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Background <p>Contact allergens typically trigger localised reactions, but systemic Type I hypersensitivity from skin contact reactions are rare.</p> Case presentation <p>We present the case of a 69-year-old non-atopic male who developed anaphylaxis following the application of moisturizer to an area of chemical burns. Skin testing showed a strong positive result to moisturizer. Whilst not all ingredients were available for testing, phenoxyethanol was thought to be the likely culprit agent based on literature review and a weakly positive skin test result.</p> Conclusion <p>Products such as moisturizers can rarely trigger anaphylaxis, especially when applied to damaged skin which may favor systemic absorption. This case highlights the need for careful consideration of cosmetic application when discerning culprit allergens.</p>

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Moisturizer induced contact anaphylaxis

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年2月11日

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  • Bronte Jeffrey,
  • Logan Gardner,
  • Michelle Le,
  • Julie Frost,
  • Ming Wei Lin

摘要

Background

Contact allergens typically trigger localised reactions, but systemic Type I hypersensitivity from skin contact reactions are rare.

Case presentation

We present the case of a 69-year-old non-atopic male who developed anaphylaxis following the application of moisturizer to an area of chemical burns. Skin testing showed a strong positive result to moisturizer. Whilst not all ingredients were available for testing, phenoxyethanol was thought to be the likely culprit agent based on literature review and a weakly positive skin test result.

Conclusion

Products such as moisturizers can rarely trigger anaphylaxis, especially when applied to damaged skin which may favor systemic absorption. This case highlights the need for careful consideration of cosmetic application when discerning culprit allergens.