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Objective <p>Reference intervals (RIs) are crucial for the interpretation of results and overall patient management. There are currently no known established reference values for haematological parameters for patients with sickle cell anaemia (SCA) in Nigeria, making it difficult for clinicians to interpret and diagnose abnormalities appropriately. This study aimed at establishing RIs of some haematological indices for individuals with SCA.</p> Results <p>Generally, the reference interval for Haematocrit (%) is 17.8 to 29.7, while the WBC (x 10<sup>9</sup>/l) ranged between 5.9 and 12.1 and the platelet count (x 10<sup>9</sup>/l) is 166–465. For the male participants, the reference interval for haematocrit (%) was found to be between 17.8 and 29, the WBC (x 10<sup>9</sup>/l) ranged between 6.7 and 12.1 and the platelet count (x 10<sup>9</sup>/l) was between 166 and 399. The female subjects had a haematocrit (%) of between 18.7 and 28.5, WBC of between 5.9 10<sup>9</sup>/l and 13.0 × 10<sup>9</sup>/l and the platelet count (x 10<sup>9</sup>/l) was between 225 and 465.</p>

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Reference intervals of haematological indices for young adults with sickle cell anaemia in Southwestern Nigeria

  • 期刊论文

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  • 发表日期：

    2025年5月26日

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  • Muritala A. Asafa,
  • Ibrahim O. Ahmed,
  • Mary B. Agim,
  • Taofik A. Fabinu,
  • Simeon O. Kusoro,
  • Blessing T. Ogunoye,
  • Oluwadare Ogunlade,
  • Rahman A. Bolarinwa

摘要

Objective

Reference intervals (RIs) are crucial for the interpretation of results and overall patient management. There are currently no known established reference values for haematological parameters for patients with sickle cell anaemia (SCA) in Nigeria, making it difficult for clinicians to interpret and diagnose abnormalities appropriately. This study aimed at establishing RIs of some haematological indices for individuals with SCA.

Results

Generally, the reference interval for Haematocrit (%) is 17.8 to 29.7, while the WBC (x 109/l) ranged between 5.9 and 12.1 and the platelet count (x 109/l) is 166–465. For the male participants, the reference interval for haematocrit (%) was found to be between 17.8 and 29, the WBC (x 109/l) ranged between 6.7 and 12.1 and the platelet count (x 109/l) was between 166 and 399. The female subjects had a haematocrit (%) of between 18.7 and 28.5, WBC of between 5.9 109/l and 13.0 × 109/l and the platelet count (x 109/l) was between 225 and 465.