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Objective <p>This study aimed to investigate the sociodemographic, clinical and renal correlates associated with severe anaemia among people with HIV.</p> Methods <p>We conducted a cross-sectional analysis of people with HIV on antiretroviral therapy (ART) for at least 6 months, stratified by anaemia status. Anaemia was defined based on the World Health Organisation (WHO) classification, as haemoglobin concentration lower than normal i.e. &lt;12&#xa0;g/dl in females and &lt; 13&#xa0;g/dl in males and the primary outcome, severe anaemia, as a haemoglobin level below 8&#xa0;g/dl according to the World Health Organisation.</p> Results <p>The study comprised 372 participants receiving ART, of whom 236 (63.4%) were females. The mean age ± SD of the participants was 44.8 ± 12.4 years. The overall prevalence of severe anaemia was 7.8% (95% CI: 0.053–0.111). In multivariable logistic regression analysis, factors significantly associated with severe anaemia were female sex (Adjusted Odds Ratio (AOR: 14.3, 95% CI: 2.14–126.6), albumin (AOR: 0.93 95% CI: 0.88–0.98) and creatinine levels (AOR: 1.01 95% CI: 1.00-1.03).</p>

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Severe anaemia in people with HIV: demographic, clinical and renal correlates

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年2月3日

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  • Kingsley Kamvuma,
  • Sody Munsaka,
  • Sepiso K. Masenga,
  • John Amos Mulemena,
  • Christopher Newton Phiri,
  • Michelo Miyoba,
  • Benson M. Hamooya

摘要

Objective

This study aimed to investigate the sociodemographic, clinical and renal correlates associated with severe anaemia among people with HIV.

Methods

We conducted a cross-sectional analysis of people with HIV on antiretroviral therapy (ART) for at least 6 months, stratified by anaemia status. Anaemia was defined based on the World Health Organisation (WHO) classification, as haemoglobin concentration lower than normal i.e. <12 g/dl in females and < 13 g/dl in males and the primary outcome, severe anaemia, as a haemoglobin level below 8 g/dl according to the World Health Organisation.

Results

The study comprised 372 participants receiving ART, of whom 236 (63.4%) were females. The mean age ± SD of the participants was 44.8 ± 12.4 years. The overall prevalence of severe anaemia was 7.8% (95% CI: 0.053–0.111). In multivariable logistic regression analysis, factors significantly associated with severe anaemia were female sex (Adjusted Odds Ratio (AOR: 14.3, 95% CI: 2.14–126.6), albumin (AOR: 0.93 95% CI: 0.88–0.98) and creatinine levels (AOR: 1.01 95% CI: 1.00-1.03).