Objectives <p>Health-Significant Quality of Life Measure (Health-SigQOLM) provides a generic and dynamic assessment of Health-related quality of life (HRQOL). This study aims to assess the HRQOL among healthy and non-healthy participants with varying chronic diseases.</p> Results <p>Comparisons between healthy and non-healthy participants revealed statistically significant differences (<i>p</i> &lt; 0.001) in the mean overall HRQOL score as well as across all its nine domains. Therefore, the Health-SigQOLM, along with its nine domains, is demonstrated to have adequate sensitivity in distinguishing between healthy and non-healthy study participants. This had supported the evidence that the Health-SigQOLM is a reliable and valid scale for measuring both generic and dynamic HRQOL.</p>

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A generic and dynamic measure of health-related quality of life across a variety of health and disease conditions: insights from healthy individuals and patients with a variety of diagnoses

  • Mohamad Adam Bujang,
  • Wei Hong Lai,
  • Xun Ting Tiong,
  • Alex Ren Jye Kim,
  • Masliyana Husin,
  • Yvonne Yih Huan Jee,
  • Nurul Fatma Diyana Ahmad,
  • Clare Hui Hong Tan,
  • Khoo Sing Yee,
  • Yoon Khee Hon,
  • Cheng Hoon Chew,
  • Eileen Pin Pin Yap,
  • Fazalena Johari,
  • Alan Yean Yip Fong

摘要

Objectives

Health-Significant Quality of Life Measure (Health-SigQOLM) provides a generic and dynamic assessment of Health-related quality of life (HRQOL). This study aims to assess the HRQOL among healthy and non-healthy participants with varying chronic diseases.

Results

Comparisons between healthy and non-healthy participants revealed statistically significant differences (p < 0.001) in the mean overall HRQOL score as well as across all its nine domains. Therefore, the Health-SigQOLM, along with its nine domains, is demonstrated to have adequate sensitivity in distinguishing between healthy and non-healthy study participants. This had supported the evidence that the Health-SigQOLM is a reliable and valid scale for measuring both generic and dynamic HRQOL.