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Background <p>Academic stress can significantly impact glycemic outcome and psychological well-being in adolescents with type 1diabetes (T1D).</p> Objectives <p>To evaluate the role of MiniMed™ 780G insulin pump in managing exam-induced glycemic deterioration among high school students with T1D.</p> Subjects and methods <p>This prospective study included 53 adolescents with T1D using MiniMed™ 780G insulin pump. Participants were monitored during routine academic and exam periods. Psychological stress was measured using the Perceived Stress Scale (PSS-10), Hamilton Anxiety Rating Scale (HAM-A) and Hamilton Depression Rating Scale (HAM-D). Serum cortisol level was assessed and continuous glucose monitoring (CGM) data were monitored. Paired t-test and Wilcoxon test were used for parametric and non-parametric data, respectively to identify changes in study variables between study periods. A p value &lt; 0.05 was considered statistically significant.</p> Results <p>Although PSS-10, HAM-A and HAM-D scores as well as serum cortisol level (15.7 ± 4.6 versus 8.6 ± 3.1&#xa0;µg/dL) were elevated in high school students with T1D during exam period compared with baseline values (<i>p</i> &lt; 0.001); however, no significant change was found as regards mean sensor glucose (153.23 ± 14.1 versus 147.51 ± 13.7&#xa0;mg/dL; <i>p</i> = 0.561), coefficient of variation (35.11 ± 8.0 versus 32.81 ± 8.2%; <i>p</i> = 0.167), time in range (TIR) (75.10 ± 8.8 versus 78.20 ± 9.0%; <i>p</i> = 0.086) and time in tight range (58.50 ± 7.0 versus 60.10 ± 7.5%; <i>p</i> = 0.311) which corresponds with the significant increase in auto basal and auto correction insulin delivery of MiniMed™ 780G (<i>p</i> &lt; 0.001).</p> Conclusion <p>The automated adaptive algorithm of the MiniMed™ 780G system mitigated exams-related stress hyperglycemia, reducing glycemic variability and successfully maintaining the recommended glycemic outcomes with a TIR greater than 70% throughout the exam period.</p>

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Mind–glucose control interplay in type 1 diabetes: management of exam-related stress using the MiniMed™ 780G insulin pump among high school students

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年3月18日

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  • Nancy Samir Elbarbary,
  • Nahla Nagy,
  • Lena Ahmed Ismail,
  • Sarah Ashraf Abouelnasr,
  • Eman Abdel Rahman Ismail

摘要

Background

Academic stress can significantly impact glycemic outcome and psychological well-being in adolescents with type 1diabetes (T1D).

Objectives

To evaluate the role of MiniMed™ 780G insulin pump in managing exam-induced glycemic deterioration among high school students with T1D.

Subjects and methods

This prospective study included 53 adolescents with T1D using MiniMed™ 780G insulin pump. Participants were monitored during routine academic and exam periods. Psychological stress was measured using the Perceived Stress Scale (PSS-10), Hamilton Anxiety Rating Scale (HAM-A) and Hamilton Depression Rating Scale (HAM-D). Serum cortisol level was assessed and continuous glucose monitoring (CGM) data were monitored. Paired t-test and Wilcoxon test were used for parametric and non-parametric data, respectively to identify changes in study variables between study periods. A p value < 0.05 was considered statistically significant.

Results

Although PSS-10, HAM-A and HAM-D scores as well as serum cortisol level (15.7 ± 4.6 versus 8.6 ± 3.1 µg/dL) were elevated in high school students with T1D during exam period compared with baseline values (p < 0.001); however, no significant change was found as regards mean sensor glucose (153.23 ± 14.1 versus 147.51 ± 13.7 mg/dL; p = 0.561), coefficient of variation (35.11 ± 8.0 versus 32.81 ± 8.2%; p = 0.167), time in range (TIR) (75.10 ± 8.8 versus 78.20 ± 9.0%; p = 0.086) and time in tight range (58.50 ± 7.0 versus 60.10 ± 7.5%; p = 0.311) which corresponds with the significant increase in auto basal and auto correction insulin delivery of MiniMed™ 780G (p < 0.001).

Conclusion

The automated adaptive algorithm of the MiniMed™ 780G system mitigated exams-related stress hyperglycemia, reducing glycemic variability and successfully maintaining the recommended glycemic outcomes with a TIR greater than 70% throughout the exam period.