Scholarlink

<p>Chronic inflammatory arthritis of childhood, known as juvenile idiopathic arthritis (JIA), exhibits distinct and shared features with adult-onset disease. Recent advances in minimally invasive synovial biopsy, high resolution imaging and sequencing technologies have enabled detailed characterisation of the inflamed synovium in JIA, facilitating insights into the underlying immunopathology. In this review we draw on these findings to consider how the developing immunological and structural context of the joint impacts the presentation and consequence of inflammatory joint disease in children and young adults.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Novel insights into the biology of childhood arthritis- lessons learned from the synovium

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年12月20日

查看全文
  • Chrissy Bolton,
  • Margaret H. Chang

摘要

Chronic inflammatory arthritis of childhood, known as juvenile idiopathic arthritis (JIA), exhibits distinct and shared features with adult-onset disease. Recent advances in minimally invasive synovial biopsy, high resolution imaging and sequencing technologies have enabled detailed characterisation of the inflamed synovium in JIA, facilitating insights into the underlying immunopathology. In this review we draw on these findings to consider how the developing immunological and structural context of the joint impacts the presentation and consequence of inflammatory joint disease in children and young adults.