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<p>Advances in the field of three-dimensional (3D) genomics have revealed an ever-expanding array of architectural features that were unknown only a few years ago. Just as ribbon diagrams integrate spatial and symbolic representation to communicate the shape of a protein, the representation of genomes in 3D space requires the development and use of new cartographic symbols and visual conventions. Here, we propose a conceptualized grammar that makes it easier to create visual 3D representations of genomes.</p>

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Geometric Diagrams of Genomes: constructing a visual grammar for 3D genomics

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年6月26日

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  • Carla Molins-Pitarch,
  • Jonathan Khao,
  • Santiago Bonet,
  • Yolanda Justicia,
  • Clementina Altube,
  • Mike Goodstadt,
  • Francesc Ribot,
  • Erez Lieberman Aiden,
  • Nicola Neretti,
  • Gaël G. McGill,
  • Marc A. Marti-Renom

摘要

Advances in the field of three-dimensional (3D) genomics have revealed an ever-expanding array of architectural features that were unknown only a few years ago. Just as ribbon diagrams integrate spatial and symbolic representation to communicate the shape of a protein, the representation of genomes in 3D space requires the development and use of new cartographic symbols and visual conventions. Here, we propose a conceptualized grammar that makes it easier to create visual 3D representations of genomes.