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<p>Despite the progress made in the last few decades in diagnosis and therapy, children and adolescents still die of asthma worldwide. In this study, we collected all asthma-related death events in Italian children and adolescents (0–19 years old) from 2013 to 2023 through the Italian National Statistical Database. 46 deaths were recorded, with a mortality rate of 0.39 per million individuals aged 0–19 years old (population denominator: 10.7&#xa0;million), with the highest number of deaths observed in North-East Regions (36.9%) and 39/46 (84.7%) deaths between 10 and 19 years old. Factors associated with fatal asthma are also discussed. Targeted preventive strategies and further research are called for, particularly in high-incidence regions and adolescents.</p>

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Asthma-related mortality in Italian children and adolescents

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年8月5日

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  • Francesca Saretta,
  • Mattia Giovannini,
  • Angela Klain,
  • Luca Pecoraro,
  • Stefania Arasi,
  • Simona Barni,
  • Lucia Caminiti,
  • Riccardo Castagnoli,
  • Mariannita Gelsomino,
  • Lucia Liotti,
  • Carla Mastrorilli,
  • Francesca Mori,
  • Gianluigi Marseglia,
  • Elio Novembre

摘要

Despite the progress made in the last few decades in diagnosis and therapy, children and adolescents still die of asthma worldwide. In this study, we collected all asthma-related death events in Italian children and adolescents (0–19 years old) from 2013 to 2023 through the Italian National Statistical Database. 46 deaths were recorded, with a mortality rate of 0.39 per million individuals aged 0–19 years old (population denominator: 10.7 million), with the highest number of deaths observed in North-East Regions (36.9%) and 39/46 (84.7%) deaths between 10 and 19 years old. Factors associated with fatal asthma are also discussed. Targeted preventive strategies and further research are called for, particularly in high-incidence regions and adolescents.