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<p>This study evaluates the accuracy of ChatGPT in generating chromosomal representations (formulas)&#xa0;based on ISCN rules in clinical cytogenetics. While ChatGPT generated correct answers for simple cases, it frequently failed in complex cases. These findings highlight the limitations of current AI tools in accurate clinical cytogenetic reporting, reinforcing the vital role of skilled clinical cytogeneticists for accurate interpretation and reporting.</p>

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Assessing the reliability of ChatGPT in cytogenetic reporting and interpretation: implications for clinical use

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年7月18日

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  • Alain Chebly,
  • Lauren Veronese,
  • Edith Chevret

摘要

This study evaluates the accuracy of ChatGPT in generating chromosomal representations (formulas) based on ISCN rules in clinical cytogenetics. While ChatGPT generated correct answers for simple cases, it frequently failed in complex cases. These findings highlight the limitations of current AI tools in accurate clinical cytogenetic reporting, reinforcing the vital role of skilled clinical cytogeneticists for accurate interpretation and reporting.