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<p>Pleural lipomas are rare benign intrathoracic mesenchymal neoplasms. Although typically asymptomatic, they can enlarge and cause symptoms secondary to compression of surrounding intrathoracic structures. There is minimal reporting of pleural lipoma observed with computed tomography throughout prolonged periods of surveillance; therefore, differentiating well-differentiated malignant liposarcoma from imaging alone remains a diagnostic challenge. We present the case of a 74 year-old male with tobacco use and asbestos exposure who underwent surveillance of a pleural neoplasm over 9 years. Continued enlargement and morphological changes concerning for malignancy prompted video-assisted thoracoscopic surgical resection. The pleural mass was diagnosed as a pleural lipoma and the patient recovered well. Pleural lipomas, especially in patients with risk factors for malignancy, should be resected for accurate diagnosis and prevention of complications associated with compression of adjacent structures.</p>

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Surgical resection of pleural lipoma after 9 years of serial imaging

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年3月1日

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  • Chadi Nahal,
  • Chetna Purohit,
  • Andrew Toma,
  • Peter Seirafi

摘要

Pleural lipomas are rare benign intrathoracic mesenchymal neoplasms. Although typically asymptomatic, they can enlarge and cause symptoms secondary to compression of surrounding intrathoracic structures. There is minimal reporting of pleural lipoma observed with computed tomography throughout prolonged periods of surveillance; therefore, differentiating well-differentiated malignant liposarcoma from imaging alone remains a diagnostic challenge. We present the case of a 74 year-old male with tobacco use and asbestos exposure who underwent surveillance of a pleural neoplasm over 9 years. Continued enlargement and morphological changes concerning for malignancy prompted video-assisted thoracoscopic surgical resection. The pleural mass was diagnosed as a pleural lipoma and the patient recovered well. Pleural lipomas, especially in patients with risk factors for malignancy, should be resected for accurate diagnosis and prevention of complications associated with compression of adjacent structures.