Scholarlink

Background <p>The thin labial alveolar wall (LAW) of anterior maxillary teeth is prone to resorption after flap surgery, jeopardizing aesthetic outcomes. This study evaluated whether extended guided bone regeneration (GBR) to cover the LAW of adjacent teeth mitigates this bone loss.</p> Methods <p>In this retrospective cohort study, we categorized adjacent teeth into three groups according to the intraoperative extension of the graft relative to the LAW: Non-Extended GBR (NE-GBR; graft confined to edentulous site), Partially Extended GBR (PE-GBR; graft on partial BBW), and Fully Extended GBR (FE-GBR; graft covering BBW to the crest). Horizontal LAW thickness and vertical distance from cementoenamel junction to the alveolar crest were measured on superimposed pre-operative and 6-month post-operative CBCT scans.</p> Results <p>Analysis included 135 adjacent teeth (80 patients). Significant horizontal resorption occurred in the NE-GBR (− 0.40 ± 0.32&#xa0;mm) and PE-GBR (− 0.43 ± 0.44&#xa0;mm) groups (<i>p</i> &lt; 0.001), while the FE-GBR group maintained stable dimensions (0.15 ± 0.75&#xa0;mm, <i>p</i> = 0.523). Vertically, the FE-GBR group showed a significant dimensional gain (0.43 ± 1.10&#xa0;mm, <i>p</i> &lt; 0.001), unlike the resorption seen in other groups. Mixed-effects models confirmed FE-GBR as a significant positive predictor for both horizontal (β = 0.48, <i>p</i> &lt; 0.001) and vertical (β = 0.48, <i>p</i> = 0.001) dimensional preservation.</p> Conclusions <p>Fully extended GBR to cover the LAW up to the crest appears to counteract post-surgical reduction, better preserving radiographic alveolar ridge dimensions in the aesthetic zone over a 6-month period.</p> Trial registration <p>This study protocol was approved by the Institutional Review Board (LCYJ20250303005) and was registered in the Chinese Clinical Trial Registry (ChiCTR2500099603).</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Effects of extended guided bone regeneration on the labial alveolar wall of adjacent teeth in the anterior maxilla: a retrospective cohort study

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年4月29日

查看全文
  • Xingchao Zeng,
  • Hao Chen,
  • Yifan Jiang,
  • Yuting Wen,
  • Jiaxin Luo,
  • Fuchun Chen,
  • Bin Chen,
  • Shiyong Zhao,
  • Tong Xi

摘要

Background

The thin labial alveolar wall (LAW) of anterior maxillary teeth is prone to resorption after flap surgery, jeopardizing aesthetic outcomes. This study evaluated whether extended guided bone regeneration (GBR) to cover the LAW of adjacent teeth mitigates this bone loss.

Methods

In this retrospective cohort study, we categorized adjacent teeth into three groups according to the intraoperative extension of the graft relative to the LAW: Non-Extended GBR (NE-GBR; graft confined to edentulous site), Partially Extended GBR (PE-GBR; graft on partial BBW), and Fully Extended GBR (FE-GBR; graft covering BBW to the crest). Horizontal LAW thickness and vertical distance from cementoenamel junction to the alveolar crest were measured on superimposed pre-operative and 6-month post-operative CBCT scans.

Results

Analysis included 135 adjacent teeth (80 patients). Significant horizontal resorption occurred in the NE-GBR (− 0.40 ± 0.32 mm) and PE-GBR (− 0.43 ± 0.44 mm) groups (p < 0.001), while the FE-GBR group maintained stable dimensions (0.15 ± 0.75 mm, p = 0.523). Vertically, the FE-GBR group showed a significant dimensional gain (0.43 ± 1.10 mm, p < 0.001), unlike the resorption seen in other groups. Mixed-effects models confirmed FE-GBR as a significant positive predictor for both horizontal (β = 0.48, p < 0.001) and vertical (β = 0.48, p = 0.001) dimensional preservation.

Conclusions

Fully extended GBR to cover the LAW up to the crest appears to counteract post-surgical reduction, better preserving radiographic alveolar ridge dimensions in the aesthetic zone over a 6-month period.

Trial registration

This study protocol was approved by the Institutional Review Board (LCYJ20250303005) and was registered in the Chinese Clinical Trial Registry (ChiCTR2500099603).