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Objective <p>Ventilator-associated pneumonia (VAP) remains a major complication in mechanically ventilated patients. This study aims to evaluate the clinical efficacy of a gravity-weighted continuous oral suction dental pad in preventing VAP.</p> Methods <p>This single-center, retrospective, pre-post cohort study included 118 intensive care unit (ICU) patients undergoing mechanical ventilation. Patients admitted before June 2024 received conventional dental pads (control group, <i>n</i> = 59), while those admitted thereafter received the novel device (intervention group, <i>n</i> = 59). Oral hygiene, inflammatory markers, and VAP incidence were compared between groups.</p> Results <p>At 72&#xa0;h post-intubation, the intervention group showed significantly lower C-reactive protein (CRP) [58.0 (34.45–75.80) vs. 83.7 (47.35-142.55) mg/L], white blood cell (WBC) [8.1 (6.20–9.75) vs. 10.2 (8.1–14.0) ×10⁹/L], oral cleanliness scores [11 (10–11) vs. 13 (12–15)], and Clinical Pulmonary Infection Score (CPIS) scores [5 (2–6) vs. 5 (4–8)] (all <i>P</i> &lt; 0.01). VAP occurred in 2 (3.39%) patients in the intervention group and 9 (15.25%) in the control group (<i>P</i> = 0.019). Kaplan-Meier analysis showed a lower 7-day cumulative incidence of VAP in the intervention group (log-rank <i>P</i> = 0.0021).</p> Conclusion <p>The gravity-weighted continuous oral suction dental pad may improve oral hygiene and reduce early VAP incidence in mechanically ventilated patients. Further multicenter prospective studies are warranted.</p>

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Clinical application of a novel gravity-weighted continuous oral suction dental pad in preventing ventilator-associated pneumonia in intubated patients

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年4月22日

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  • Xiaolan Guo,
  • Yang Chen,
  • Pan Li,
  • Fangfang Yu,
  • Yifeng Chen

摘要

Objective

Ventilator-associated pneumonia (VAP) remains a major complication in mechanically ventilated patients. This study aims to evaluate the clinical efficacy of a gravity-weighted continuous oral suction dental pad in preventing VAP.

Methods

This single-center, retrospective, pre-post cohort study included 118 intensive care unit (ICU) patients undergoing mechanical ventilation. Patients admitted before June 2024 received conventional dental pads (control group, n = 59), while those admitted thereafter received the novel device (intervention group, n = 59). Oral hygiene, inflammatory markers, and VAP incidence were compared between groups.

Results

At 72 h post-intubation, the intervention group showed significantly lower C-reactive protein (CRP) [58.0 (34.45–75.80) vs. 83.7 (47.35-142.55) mg/L], white blood cell (WBC) [8.1 (6.20–9.75) vs. 10.2 (8.1–14.0) ×10⁹/L], oral cleanliness scores [11 (10–11) vs. 13 (12–15)], and Clinical Pulmonary Infection Score (CPIS) scores [5 (2–6) vs. 5 (4–8)] (all P < 0.01). VAP occurred in 2 (3.39%) patients in the intervention group and 9 (15.25%) in the control group (P = 0.019). Kaplan-Meier analysis showed a lower 7-day cumulative incidence of VAP in the intervention group (log-rank P = 0.0021).

Conclusion

The gravity-weighted continuous oral suction dental pad may improve oral hygiene and reduce early VAP incidence in mechanically ventilated patients. Further multicenter prospective studies are warranted.