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Background <p>The burden of non-communicable diseases (NCDs) is rising in Iran, contributing to many years of quality of life lost and premature deaths. Monitroing NCDs and related risk factors are crucial for prevention and resource allocation.</p> Objectives <p>This article describes the study design, progress, and baseline characteristics of the Qazvin Employees’ Health Cohort Study.</p> Methods <p>In this cohort study, eligible participants were employees of the Qazvin University of Medical Sciences, Qazvin, Iran. Data were collected through interviews and physical exams, covering various health aspects. Participants will be followed annually using telephone interviews to track their health outcomes. Descriptive statistics, t-tests, and χ² analyses were conducted using Stata, version 14.</p> Results <p>Between 2021 and 2022, 1,250 adult employees (% 56.56 males) were recruited. Thyroid disease (20.6% vs. 4.9%, <i>p</i> &lt; 0.001), depression (9.4% vs. 5.3%, <i>p</i> = 0.014), and chronic headache (12.1% vs. 5.2%, <i>p</i> &lt; 0.001) were more frequently observed among women. In contrast, kidney stones (<i>p</i> &lt; 0.001), elevated systolic and diastolic blood pressure (<i>p</i> &lt; 0.001) were more prevalent among men. Also, women had significantly more favorable biochemical profiles than men in red blood cell indices, triglycerides, SGOT, and HDL cholesterol (all <i>p</i> &lt; 0.001).</p> Conclusions <p>This study provides insights into NCD prevalence and risk factors among employees. It emphasizes that sex is a significant determinant of both morbidity and metabolic health, underscoring the need for sex-specific approaches in clinical assessment, preventive care, and targeted interventions to address differential risk profiles and promote healthier lifestyles. Future phases will address gaps, add data, and integrate with the Iran Cohort Consortium.</p>

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Cohort profile of a longitudinal study on non-communicable diseases in employees in northwest Iran

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年7月2日

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  • Manoochehr Mahram,
  • Elahe Jafari,
  • Amin Yazdani,
  • Soudabeh Alatab,
  • Atefeh Khoshkchali,
  • Mohammad Amerzadeh,
  • Abouzar Raeisvandi,
  • Mehdi Osooli,
  • Zahra Hosseinkhani

摘要

Background

The burden of non-communicable diseases (NCDs) is rising in Iran, contributing to many years of quality of life lost and premature deaths. Monitroing NCDs and related risk factors are crucial for prevention and resource allocation.

Objectives

This article describes the study design, progress, and baseline characteristics of the Qazvin Employees’ Health Cohort Study.

Methods

In this cohort study, eligible participants were employees of the Qazvin University of Medical Sciences, Qazvin, Iran. Data were collected through interviews and physical exams, covering various health aspects. Participants will be followed annually using telephone interviews to track their health outcomes. Descriptive statistics, t-tests, and χ² analyses were conducted using Stata, version 14.

Results

Between 2021 and 2022, 1,250 adult employees (% 56.56 males) were recruited. Thyroid disease (20.6% vs. 4.9%, p < 0.001), depression (9.4% vs. 5.3%, p = 0.014), and chronic headache (12.1% vs. 5.2%, p < 0.001) were more frequently observed among women. In contrast, kidney stones (p < 0.001), elevated systolic and diastolic blood pressure (p < 0.001) were more prevalent among men. Also, women had significantly more favorable biochemical profiles than men in red blood cell indices, triglycerides, SGOT, and HDL cholesterol (all p < 0.001).

Conclusions

This study provides insights into NCD prevalence and risk factors among employees. It emphasizes that sex is a significant determinant of both morbidity and metabolic health, underscoring the need for sex-specific approaches in clinical assessment, preventive care, and targeted interventions to address differential risk profiles and promote healthier lifestyles. Future phases will address gaps, add data, and integrate with the Iran Cohort Consortium.