Background <p>Influenza A H1N1 is a contagious viral infection caused by Influenza A virus subtypes (most commonly H1N1). This study analyses patient data from the Influenza A H1N1 cases reported in Punjab, India, for the years 2022, 2023, and 2024, focusing on distribution patterns, demographic characteristics, and mortality trends.</p> Methods <p>This retrospective, record-based study included data on the epidemiological characteristics of Influenza A H1N1 cases in the years 2022, 2023, and 2024 which were descriptively analysed using data from the Integrated Disease Surveillance Programme (Directorate of Health and Family Welfare, Punjab).</p> Results <p>The analysis revealed a higher incidence among adults aged 51–70 years and district Ludhiana reported the highest number of cases. It also marks the seasonal shift in the pattern of virus outbreaks.</p> Conclusion <p>This study reveals a marked seasonal shift in the incidence of Influenza A H1N1 in Punjab, with a higher prevalence among individuals aged 51–70 years. The findings underline the importance of targeted vaccination campaigns before peak months for high-risk groups and year-round surveillance as well as close caution should be exercised in H1N1 patients with co‑morbidities.</p>