Scholarlink

Introduction <p>This study aims to estimate the disease burden of hip osteoarthritis(OA) from 1990 to 2021, disaggregated by regions, age groups, genders and the Socio-Demographic Index(SDI), and to predict long-term trends over the next 30&#xa0;years.</p> Materials and methods <p>Using data from the Global Burden of Disease (GBD) 2021 database, incidence, prevalence, and disability-adjusted life years (DALYs) of hip OA were analyzed at all geographical levels. Decomposition analysis attributed overall differences to population growth, aging, and epidemiological changes. Temporal trends and future disease burden were described using Estimated Annual Percentage Change (EAPC) and Bayesian Age-Period-Cohort(BAPC) models.</p> Results <p>Global disease burden of hip OA increased from 1990 to 2021. Among the 21 GBD regions, South Asia experienced the highest rise in age-standardized DALY rates (EAPC = 0.94, 95% UI: 0.88–1.00), while East Asia had the largest increases in age-standardized incidence rates (ASIR) (EAPC = 1.00, 95% UI: 0.92–1.09) and age-standardized prevalence rates (ASPR) (EAPC = 3.32, 95% UI: 3.22–3.43). Globally, five inflection points were identified in age-standardized DALYs rates, ASIR, and ASPR, with declines in 1990–1995 and 2019–2021. In 2021, a positive correlation was observed between SDI and hip OA burden. Population growth was the primary driver of global variations in DALYs, incidence, and prevalence. BAPC projections indicate a continued increase in these metrics through 2050.</p> Conclusions <p>Over the past 30&#xa0;years, the burden of hip OA has steadily increased at all geographical levels, exhibiting correlations with genders, ages, and SDI. Most regions are projected to maintain an upward trend in disease burden over the next 30&#xa0;years.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Global, regional, and national disease burden of hip osteoarthritis and its predicted level to 2050: an epidemiological analysis from 1990 to 2021

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年2月20日

查看全文
  • Xinyu Liu,
  • Rujing Yang,
  • Zhexuan Zhao,
  • Dingyu Pan,
  • Xue-jie Yu

摘要

Introduction

This study aims to estimate the disease burden of hip osteoarthritis(OA) from 1990 to 2021, disaggregated by regions, age groups, genders and the Socio-Demographic Index(SDI), and to predict long-term trends over the next 30 years.

Materials and methods

Using data from the Global Burden of Disease (GBD) 2021 database, incidence, prevalence, and disability-adjusted life years (DALYs) of hip OA were analyzed at all geographical levels. Decomposition analysis attributed overall differences to population growth, aging, and epidemiological changes. Temporal trends and future disease burden were described using Estimated Annual Percentage Change (EAPC) and Bayesian Age-Period-Cohort(BAPC) models.

Results

Global disease burden of hip OA increased from 1990 to 2021. Among the 21 GBD regions, South Asia experienced the highest rise in age-standardized DALY rates (EAPC = 0.94, 95% UI: 0.88–1.00), while East Asia had the largest increases in age-standardized incidence rates (ASIR) (EAPC = 1.00, 95% UI: 0.92–1.09) and age-standardized prevalence rates (ASPR) (EAPC = 3.32, 95% UI: 3.22–3.43). Globally, five inflection points were identified in age-standardized DALYs rates, ASIR, and ASPR, with declines in 1990–1995 and 2019–2021. In 2021, a positive correlation was observed between SDI and hip OA burden. Population growth was the primary driver of global variations in DALYs, incidence, and prevalence. BAPC projections indicate a continued increase in these metrics through 2050.

Conclusions

Over the past 30 years, the burden of hip OA has steadily increased at all geographical levels, exhibiting correlations with genders, ages, and SDI. Most regions are projected to maintain an upward trend in disease burden over the next 30 years.