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Background <p>Lassa fever remains a public health concern, particularly in West Africa, mostly impacting Nigeria, with 10,098 suspected cases in 2024 and 1309 confirmed cases with 214 mortalities, indicating a case fatality rate of 16.3%. While Ondo State is the epi-centre of LF in Nigeria, this report examines Lassa fever trends in Ondo State from 2020 to 2024, its public health implications, and emerging concerns requiring immediate intervention.</p> Methods <p>Publicly available data from the situation report of the Nigeria Centre for Disease Control and Prevention on Lassa Fever was obtained from 2020 to 2024, including suspected and confirmed cases, healthcare workers infections, and mortalities. The data was analysed and visualized using line and combo charts to show trends over time.</p> Findings <p>In Ondo State, suspected and confirmed Lassa fever cases rose by about 388 and 21 cases annually from 2020 to 2024, reaching a peak in 2023 (1672 suspected; 433 confirmed). Infections among healthcare workers decreased from 20 in 2023 to 4 in 2024 at an annual rate of 1.2. Mortality decreased from 83 deaths in 2020 to 27 in 2024, a decrease of 10.9 per year. Early 2025 data, however, indicates emerging concerns, with 974 suspected, 249 confirmed, 30 deaths, and 9 HCWs affected as of week 11. A 5-year projection (2025–2029) predicts an average annual increase of 66 confirmed Lassa fever cases in Ondo State, emphasizing the emerging public health challenge.</p> Conclusion <p>The burden of Lassa fever in Ondo State reveals mortality trends, occupational hazards, and surveillance gaps, necessitating improved outbreak response, infection control, and diagnosis. To reduce Lassa fever, research on adaptive intervention, policy changes, improved surveillance, and protection for healthcare workers is highly recommended.</p>

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Trends, public health implications, and emerging concerns of Lassa fever in Ondo state, Nigeria

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年7月15日

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  • Idowu Peter Adewumi,
  • Abisola Esther Babatope,
  • Kayode Olayiwola Adepoju,
  • Abosede Mary Olaleye,
  • Damola Olanipekun Ajisafe,
  • Oluyemi Adewole Okunlola

摘要

Background

Lassa fever remains a public health concern, particularly in West Africa, mostly impacting Nigeria, with 10,098 suspected cases in 2024 and 1309 confirmed cases with 214 mortalities, indicating a case fatality rate of 16.3%. While Ondo State is the epi-centre of LF in Nigeria, this report examines Lassa fever trends in Ondo State from 2020 to 2024, its public health implications, and emerging concerns requiring immediate intervention.

Methods

Publicly available data from the situation report of the Nigeria Centre for Disease Control and Prevention on Lassa Fever was obtained from 2020 to 2024, including suspected and confirmed cases, healthcare workers infections, and mortalities. The data was analysed and visualized using line and combo charts to show trends over time.

Findings

In Ondo State, suspected and confirmed Lassa fever cases rose by about 388 and 21 cases annually from 2020 to 2024, reaching a peak in 2023 (1672 suspected; 433 confirmed). Infections among healthcare workers decreased from 20 in 2023 to 4 in 2024 at an annual rate of 1.2. Mortality decreased from 83 deaths in 2020 to 27 in 2024, a decrease of 10.9 per year. Early 2025 data, however, indicates emerging concerns, with 974 suspected, 249 confirmed, 30 deaths, and 9 HCWs affected as of week 11. A 5-year projection (2025–2029) predicts an average annual increase of 66 confirmed Lassa fever cases in Ondo State, emphasizing the emerging public health challenge.

Conclusion

The burden of Lassa fever in Ondo State reveals mortality trends, occupational hazards, and surveillance gaps, necessitating improved outbreak response, infection control, and diagnosis. To reduce Lassa fever, research on adaptive intervention, policy changes, improved surveillance, and protection for healthcare workers is highly recommended.