Background <p>Pro-choice female physicians and abortion <i>acompañantes</i>– feminist activists who provide information and accompaniment during self-managed medication abortions– each contribute to safe abortion access in Mexico. Synergistic collaboration between these actors could improve access to safe and high-quality abortion care. We explored the possibility of synergy between pro-choice female physicians and <i>acompañantes</i> in Mexico.</p> Methods <p>This qualitative research is based on feminist epistemology. We used an established framework that describes partner synergy to analyze data from three workshops held with 12 physicians and 13 acompañantes in Chiapas (<i>n</i> = 12), Baja California (<i>n</i> = 9), and Mexico City (<i>n</i> = 4). The workshops sought to foster empathy and reflection on interactions, collaborations, and synergy. Workshop dynamics included sociodrama acting and group discussions.</p> Results <p>We identified a common interest in building alliances and ideas about synergistic collaborations related to abortion care and accompaniment. Additionally, participants expressed an interest in mutual care arising from the recognition of common experiences of gender-based discrimination and violence among participants, which is a clear expression of synergistic collaboration. Our results also suggest that the pro-choice physicians do not see themselves as political actors, in contrast to the <i>acompañantes</i>, for whom their abortion work is deeply political. We describe that combating prejudice and fostering mutual recognition is necessary for successful collaborations, while the power asymmetry between physicians and <i>acompañantes</i> remains the main barrier to synergy. Finally, we determined that the workshop had an awareness-raising effect that could encourage the creation of subsequent alliances.</p> Conclusions <p>Creating spaces for meeting and exchange may foster collaborations between these actors from different worlds, which can facilitate access to safe abortions.</p>