Background <p>Loneliness has been recognised as a major global public health priority, given its strong associations with increased mortality and morbidity with physical and mental health disorders. Most solutions and strategies aimed at addressing loneliness have focused on individual-level interventions, with relatively limited attention to upstream, population-wide strategies such as public health awareness campaigns. This raises a critical question for public health: can awareness campaigns meaningfully address loneliness at a population level?</p> Results <p>This commentary examines the potential role of public health awareness campaigns in addressing loneliness, with a particular focus on stigma reduction, collective meaning-making, and social norms. Loneliness is a subjective, multifactorial experience that occurs across the life course and is shaped by diverse social, cultural, and structural factors. Population-wide campaigns therefore face unique challenges, including the risk of oversimplification, pathologisation, and reinforcing individual responsibility for what is often a socially produced experience. Drawing on evidence from population surveys, we highlight the prevalence of stigma surrounding loneliness, including negative stereotypes, reluctance to disclose loneliness, and concealment of lived experiences. We argue that awareness campaigns must move beyond information provision towards fostering empathy, normalising loneliness as a universal human signal, and promoting shared responsibility for healthy meaningful social connection. </p> Conclusion <p>While public health awareness campaigns alone cannot eliminate loneliness, they can play a critical role in reshaping societal understandings, reducing stigma, and creating a more supportive cultural environment for social connection. When theory-informed, co-designed, and rigorously evaluated, such campaigns can contribute meaningfully to population-level strategies to address loneliness.</p>