<p>Cataract surgery is a transformative procedure, rapidly restoring vision and improving quality of life with minimal complications. This study evaluates the social return on investment (SROI) of bilateral cataract surgeries performed by different nonprofit organizations across Latin America. By analyzing the experiences of patients and caregivers –including increased autonomy, confidence, and reduced caregiving burdens – this research provides an estimate of the associated social and economic benefits of these interventions. The average SROI ratios under the baseline scenario are 12:1 for patients, 11:1 for caregivers, and 9:1 for patient-caregiver pairs. Sensitivity analysis reinforces these results, with SROI ratios ranging from 3:1 to 18:1 under various assumptions about outcome duration, discount rates, and valuation of time, among other scenarios. Reduced caregiving responsibilities may create conditions for young female caregivers to pursue economic activities, potentially enhancing labor force participation. These findings suggest that nonprofits may play an important part in addressing healthcare gaps and complementing public services, particularly in underserved regions. Furthermore, by helping to address healthcare access disparities and reduce economic burdens, nonprofit cataract surgeries may represent a promising approach to improving lives across Latin America. While the study focuses on seven nonprofit organizations and a specific intervention, its results demonstrate the potential for broader applications in nonprofit healthcare delivery. Lastly, the research highlights the importance of understanding and valuing both direct and indirect benefits of healthcare interventions.</p>