Scholarlink

Background <p>Primary renal mucosa-associated lymphoid tissue (MALT) lymphoma is exceedingly rare. Although immune thrombocytopenia (ITP) may accompany lymphoproliferative disorders, its association with primary renal MALT lymphoma has not been previously reported.</p> Case presentation <p>A 60-year-old male presenting with isolated thrombocytopenia was diagnosed with ITP during hematologic evaluation. Abdominal imaging incidentally revealed an 8.7 × 5.6&#xa0;cm renal mass. Glucocorticoid therapy successfully stabilized platelet counts, enabling nephroureterectomy. Histopathological analysis demonstrated dense small lymphocyte infiltrates, with immunohistochemical confirmation of CD20 and Bcl-2 positivity establishing a diagnosis of MALT lymphoma. At six-month follow-up, the patient maintained disease-free status without adjuvant therapy.</p> Conclusions <p>We report a rare case of concurrent primary renal MALT lymphoma and ITP, achieving sustained remission through glucocorticoid therapy and surgical resection.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Primary renal mucosa-associated lymphoid tissue lymphoma coexisting with immune thrombocytopenia

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年7月7日

查看全文
  • Jiatai He,
  • Changqi Deng,
  • Yu Huang,
  • Miao Wang,
  • Chengcheng Wei,
  • Feixiang Xu,
  • Ruokang Chen,
  • Junduo Wang,
  • Ming Yang,
  • Zhaohui Chen

摘要

Background

Primary renal mucosa-associated lymphoid tissue (MALT) lymphoma is exceedingly rare. Although immune thrombocytopenia (ITP) may accompany lymphoproliferative disorders, its association with primary renal MALT lymphoma has not been previously reported.

Case presentation

A 60-year-old male presenting with isolated thrombocytopenia was diagnosed with ITP during hematologic evaluation. Abdominal imaging incidentally revealed an 8.7 × 5.6 cm renal mass. Glucocorticoid therapy successfully stabilized platelet counts, enabling nephroureterectomy. Histopathological analysis demonstrated dense small lymphocyte infiltrates, with immunohistochemical confirmation of CD20 and Bcl-2 positivity establishing a diagnosis of MALT lymphoma. At six-month follow-up, the patient maintained disease-free status without adjuvant therapy.

Conclusions

We report a rare case of concurrent primary renal MALT lymphoma and ITP, achieving sustained remission through glucocorticoid therapy and surgical resection.