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Background <p>This observational, prospective, analytical, and cross-sectional study was designed to systematically analyze ocular biometric parameters in patients with nuclear cataract exhibiting nuclear hardness grade ≥ 3 according to the Emery-Little classification under slit-lamp examination who scheduled for phacoemulsification. Ocular biometric measurements were acquired using the IOL Master 700, a swept-source optical coherence tomography (SS-OCT) device.</p> Results <p>Age was negatively correlated with axial length (AL), anterior chamber depth (ACD), white-to-white (WTW), and pupil diameter (PD) (r<sub>AL</sub> = − 0.13, r<sub>ACD</sub> = − 0.26, r<sub>WTW</sub> = − 0.18, all P &lt; 0.001; r<sub>PD</sub> = − 0.09, P &lt; 0.01) but positively correlated with total steep keratometry (TKs) (r<sub>TKs</sub> = 0.13, P &lt; 0.001). AL was negatively correlated with total flat keratometry (TKf), TKs, and WTW (r<sub>TKf</sub> = − 0.3, r<sub>TKs</sub> = − 0.27, r<sub>WTW</sub> = − 0.18, all P &lt; 0.001) but positively correlated with ACD and PD (r<sub>ACD</sub> = 0.43, r<sub>PD</sub> = 0.10, all P &lt; 0.001). Men had smaller TK and PD but larger WTW than women.</p> Conclusions <p>These findings highlight significant sex-related differences in biometric parameters among patients with nuclear cataract, which are closely related to AL and age. Considering variation with these parameters helps personalize surgical plans and prevent complications.</p>

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SS-OCT-based ocular biometric characteristics of patients with nuclear cataract

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年5月9日

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  • Zhao Xu,
  • Ke Yin,
  • Liming Wang,
  • Lijie Dong,
  • Jing Sun,
  • Aihua Liu

摘要

Background

This observational, prospective, analytical, and cross-sectional study was designed to systematically analyze ocular biometric parameters in patients with nuclear cataract exhibiting nuclear hardness grade ≥ 3 according to the Emery-Little classification under slit-lamp examination who scheduled for phacoemulsification. Ocular biometric measurements were acquired using the IOL Master 700, a swept-source optical coherence tomography (SS-OCT) device.

Results

Age was negatively correlated with axial length (AL), anterior chamber depth (ACD), white-to-white (WTW), and pupil diameter (PD) (rAL = − 0.13, rACD = − 0.26, rWTW = − 0.18, all P < 0.001; rPD = − 0.09, P < 0.01) but positively correlated with total steep keratometry (TKs) (rTKs = 0.13, P < 0.001). AL was negatively correlated with total flat keratometry (TKf), TKs, and WTW (rTKf = − 0.3, rTKs = − 0.27, rWTW = − 0.18, all P < 0.001) but positively correlated with ACD and PD (rACD = 0.43, rPD = 0.10, all P < 0.001). Men had smaller TK and PD but larger WTW than women.

Conclusions

These findings highlight significant sex-related differences in biometric parameters among patients with nuclear cataract, which are closely related to AL and age. Considering variation with these parameters helps personalize surgical plans and prevent complications.