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Background <p>Deep cervical lymphovenous anastomosis (LVA) has been proposed as a novel surgical approach for Alzheimer’s disease (AD). However, its therapeutic efficacy remains uncertain and controversial. Family caregivers who observe patients most closely and continuously play a vital role in recognizing subtle symptom changes. Their perceptions may provide important clues to perioperative symptom and caregiving-burden changes that remain poorly understood.</p> Aims <p>To explore family caregivers’ perceptions of patients’ symptom and caregiving burden changes before and after LVA in individuals with AD.</p> Methods <p>A descriptive qualitative study was conducted with 20 family caregivers of 20 distinct patients who had undergone LVA at a tertiary hospital in Henan Province, China. Semi-structured telephone interviews were analyzed thematically using Braun and Clarke’s framework with NVivo 15.</p> Results <p>Three themes emerged, namely a spectrum of perceived postoperative symptom change trajectories; shifts in caregiving burden without added postoperative strain; sustaining hope through continued effort.</p> Conclusion <p>Caregivers reported modest postoperative changes mixed with persistent uncertainty. Future research may integrate quantitative assessments with caregiver reports to better characterize postoperative symptom changes in AD patients following LVA.</p>

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Family caregivers’ perceptions of postoperative recovery experience following deep cervical lymphovenous anastomosis in patients with Alzheimer’s disease: a qualitative study

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年4月2日

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  • Li Chen,
  • Huixian Chen,
  • Guiqing Wang,
  • Yaqin Zhang,
  • Chunhong Li,
  • Guinv He,
  • Wenqian Shi,
  • Jinlin Fan,
  • Yanjun Wang,
  • Xiaojing Guo,
  • Lang Peng,
  • Meiying Zhao,
  • Mingzi Li,
  • Xiwen Ma

摘要

Background

Deep cervical lymphovenous anastomosis (LVA) has been proposed as a novel surgical approach for Alzheimer’s disease (AD). However, its therapeutic efficacy remains uncertain and controversial. Family caregivers who observe patients most closely and continuously play a vital role in recognizing subtle symptom changes. Their perceptions may provide important clues to perioperative symptom and caregiving-burden changes that remain poorly understood.

Aims

To explore family caregivers’ perceptions of patients’ symptom and caregiving burden changes before and after LVA in individuals with AD.

Methods

A descriptive qualitative study was conducted with 20 family caregivers of 20 distinct patients who had undergone LVA at a tertiary hospital in Henan Province, China. Semi-structured telephone interviews were analyzed thematically using Braun and Clarke’s framework with NVivo 15.

Results

Three themes emerged, namely a spectrum of perceived postoperative symptom change trajectories; shifts in caregiving burden without added postoperative strain; sustaining hope through continued effort.

Conclusion

Caregivers reported modest postoperative changes mixed with persistent uncertainty. Future research may integrate quantitative assessments with caregiver reports to better characterize postoperative symptom changes in AD patients following LVA.