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Objectives <p>The aim of this study is to evaluate the second medical opinions (SMOs) clinical value for endometriosis diagnostic strategy and patient profiles, using nationwide data from a specialized French physician network dedicated to SMOs and endometriosis management.</p> Methods &amp; materials <p>We conducted an observational cohort study including patients from France who submitted a request for an SMO through a dedicated platform (<a href="https://www.deuxiemeavis.fr/">https://www.deuxiemeavis.fr/</a>) between January 1st, 2020, and March 31st, 2024. Patients completed predefined questionnaires and subsequently received a written report following the expert SMO.</p> Results <p>A total of 3,061 patients requested a SMO for endometriosis. Most patients (61.1%) declared experiencing chronic painful symptoms a negative impact on daily life, corresponding to an Eastern Cooperative Oncology Group (ECOG) score ≥ 1. Dysmenorrhea was reported by 50.7% of patients, and 69.4% reported interruption of intercourse due to pain. Among the 2,987 patients with a complete medical record, the SMO modified the diagnosis in 51.1% of cases. After SMO, experts were unable to establish a conclusion in only 5.0% of cases, compared to 24.7% after the first medical opinion. For patients finally diagnosed with endometriosis, the SMO provided a diagnosis at a mean of 3.8 ± 1.5 years after symptom onset.</p> Conclusion <p>Seeking a SMO with access to medical experts can be essential for patients dealing with painful symptoms unsuccessfully treated, or other problems such as endometriosis diagnosis.</p>

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Diagnostic discrepancies and clinical value of second medical opinions (SMO) for endometriosis: a nationwide study analysis

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年12月15日

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  • Constance Durant des Aulnois,
  • Elie Zerbib,
  • Hélène Barberousse,
  • Pierre Panel,
  • Isabelle Holway,
  • Corinne Balleyguier,
  • Alexandre Bellucci,
  • Téodor Grand,
  • Jonathan Zerbib,
  • Corinne Bordonné,
  • Thibault Carteret,
  • Anne-Coline Monseau-Thiburce,
  • Sophie Gehin,
  • Erick Petit,
  • Marie Ceccarelli,
  • Anne-Marie Tardivel,
  • Shahed Borojeni,
  • Sarah Eskenazi,
  • Jean-Philippe Estrade,
  • François Guillibert,
  • Ludovic Friederich,
  • Elise Furet,
  • Vincent Lavoue,
  • Benjamin Merlot,
  • Paul Pirtea,
  • Sophie Warembourg,
  • Hélène Creux,
  • Yohann Dabi,
  • Sofiane Bendifallah

摘要

Objectives

The aim of this study is to evaluate the second medical opinions (SMOs) clinical value for endometriosis diagnostic strategy and patient profiles, using nationwide data from a specialized French physician network dedicated to SMOs and endometriosis management.

Methods & materials

We conducted an observational cohort study including patients from France who submitted a request for an SMO through a dedicated platform (https://www.deuxiemeavis.fr/) between January 1st, 2020, and March 31st, 2024. Patients completed predefined questionnaires and subsequently received a written report following the expert SMO.

Results

A total of 3,061 patients requested a SMO for endometriosis. Most patients (61.1%) declared experiencing chronic painful symptoms a negative impact on daily life, corresponding to an Eastern Cooperative Oncology Group (ECOG) score ≥ 1. Dysmenorrhea was reported by 50.7% of patients, and 69.4% reported interruption of intercourse due to pain. Among the 2,987 patients with a complete medical record, the SMO modified the diagnosis in 51.1% of cases. After SMO, experts were unable to establish a conclusion in only 5.0% of cases, compared to 24.7% after the first medical opinion. For patients finally diagnosed with endometriosis, the SMO provided a diagnosis at a mean of 3.8 ± 1.5 years after symptom onset.

Conclusion

Seeking a SMO with access to medical experts can be essential for patients dealing with painful symptoms unsuccessfully treated, or other problems such as endometriosis diagnosis.