Objectives <p>To explore the clinical relevant factors of patients with recurrent and non-recurrent abdominal wall endometriosis after surgical treatment, to further study the relevant risk factors of abdominal wall endometriosis recurrence, and to provide a clinical basis for reducing the recurrence of abdominal wall endometriosis in the future.</p> Methods <p>A retrospective analysis involving 501 patients with biopsy-confirmed abdominal wall endometriosis who underwent surgical treatment in the Affiliated Hospital of Jining Medical College from January 2016 to July 2022. Clinical data, postoperative recurrence, and follow-up information were collected.</p> Results <p>A total of 501 patients were included in this study, 103 patients were excluded. 398 cases of abdominal endometriosis were followed up, of which 34 cases had relapsed, with a recurrence rate of 8.54%. The median time to relapse was 16.00 (3.00–65.00) months.Compared with the non-recurrent group and the recurrent group, the recurrent group had more cesarean sections, longer operation time, more intraoperative blood loss, and more peritoneal lesions. The association between the number of cesarean delivery, as well as other covariates, and recurrence was shown according to univariate regression analysis. The number of cesarean section, the duration of operation, and the amount of intraoperative bleeding were positively correlated with the recurrence of abdominal wall endometriosis (<i>P</i> &lt; 0.05). According to the.</p>