Scholarlink

Background <p>This study evaluates and compares the mechanical behavior of two collagen membranes in an in vitro model simulating membrane-stabilized horizontal guided bone regeneration (GBR).</p> Materials and methods <p>Megreen<sup>®</sup> (bovine pericardium, BP) and Bio-Gide<sup>®</sup> (porcine dermis, PD) were tested under wet conditions. Two models were developed: (1) a balloon dilation test to assess the membrane’s capability to accommodate bone graft material and (2) a bone graft compression model to evaluate tear resistance during graft compaction.</p> Results <p>In the tensile testing, BP demonstrated a significantly superior modulus of elasticity (146.71 ± 45.08 vs. 6.08 ± 2.66&#xa0;MPa), maximum load tolerance (30.71 ± 8.42 vs. 4.49 ± 1.36&#xa0;N), and tensile stress at maximum load (14.62 ± 4.01 vs. 1.61 ± 0.49 MPa; <i>p</i> &lt; 0.001). Conversely, PD achieved high tensile extension at maximum load (6.32 ± 1.93 vs. 1.64 ± 0.32&#xa0;mm) and percent tensile strain at maximum load (52.69 ± 16.03 vs. 13.63 ± 2.65%; <i>p</i> &lt; 0.001). In the balloon dilation test, PD presented a slightly greater expansion diameter (4.43 ± 0.17 vs. 4.34 ± 0.05&#xa0;mm; <i>p</i> = 0.047). In the compression model, BP significantly outperformed PD in maximum load (40.86 ± 4.54 vs. 7.90 (7.72–10.92) N) and displacement at maximum load (5.61 ± 0.60 vs. 3.65 ± 0.82&#xa0;mm; <i>p</i> &lt; 0.001).</p> Conclusions <p>BP exhibited higher tensile strength and compression resistance, whereas PD showed greater deformability. These findings indicate distinct mechanical differences between the two collagen membranes under the tested conditions and may provide a mechanical basis for membrane selection in membrane-stabilized horizontal GBR.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Comparative mechanical analysis of collagen membranes derived from different tissues in an in vitro model simulating membrane-stabilized horizontal GBR

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年6月20日

查看全文
  • Xueying Bai,
  • Yufei Xue,
  • Jiao Li,
  • Yi Liu,
  • Zhou Ye,
  • Huiyi Yan,
  • Yi Zhou

摘要

Background

This study evaluates and compares the mechanical behavior of two collagen membranes in an in vitro model simulating membrane-stabilized horizontal guided bone regeneration (GBR).

Materials and methods

Megreen® (bovine pericardium, BP) and Bio-Gide® (porcine dermis, PD) were tested under wet conditions. Two models were developed: (1) a balloon dilation test to assess the membrane’s capability to accommodate bone graft material and (2) a bone graft compression model to evaluate tear resistance during graft compaction.

Results

In the tensile testing, BP demonstrated a significantly superior modulus of elasticity (146.71 ± 45.08 vs. 6.08 ± 2.66 MPa), maximum load tolerance (30.71 ± 8.42 vs. 4.49 ± 1.36 N), and tensile stress at maximum load (14.62 ± 4.01 vs. 1.61 ± 0.49 MPa; p < 0.001). Conversely, PD achieved high tensile extension at maximum load (6.32 ± 1.93 vs. 1.64 ± 0.32 mm) and percent tensile strain at maximum load (52.69 ± 16.03 vs. 13.63 ± 2.65%; p < 0.001). In the balloon dilation test, PD presented a slightly greater expansion diameter (4.43 ± 0.17 vs. 4.34 ± 0.05 mm; p = 0.047). In the compression model, BP significantly outperformed PD in maximum load (40.86 ± 4.54 vs. 7.90 (7.72–10.92) N) and displacement at maximum load (5.61 ± 0.60 vs. 3.65 ± 0.82 mm; p < 0.001).

Conclusions

BP exhibited higher tensile strength and compression resistance, whereas PD showed greater deformability. These findings indicate distinct mechanical differences between the two collagen membranes under the tested conditions and may provide a mechanical basis for membrane selection in membrane-stabilized horizontal GBR.