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Background <p>A three-dimensional obturation that provides a fluid tight seal of the root canal system is essential for long-term treatment success. Intracanal medicaments may hinder sealer penetration and/or affect its ability to bond with dentin. This study aimed to evaluate the sealer penetration and push-out bond strength after using Calcium hydroxide and a 2% nano-chitosan gel (CSNPs).</p> Methodology <p>Twenty-four extracted single-canal lower premolars were randomly divided, according to the intra canal medicament used, into two groups: Group A, Ca(OH)<sub>2</sub>, and Group B, 2% CSNPs. After medication placement for 1 week, all canals were sealed with gutta-percha and AH Plus sealer, mixed with 0.1% fluorescent Rhodamine B isothiocyanate. Sealer penetration was evaluated with confocal laser microscopy and then push-out bond strength was measured for both groups.</p> Results <p>For both groups, push-out bond strength varied significantly across root thirds (<i>p</i> &lt; 0.001), with higher bond strength in the coronal third. The penetration radius values were significantly greater in the CSNPs group at all root levels (<i>p</i> ≤ 0.001). At the same time, no significant differences were found between groups or among root thirds in terms of penetration area ( <i>p</i> &gt; 0.05).</p> Conclusions <p>Both Ca(OH)<sub>2</sub> and CSNPs showed comparable push-out bond strength along the root sections, with deeper, more uniform sealer penetration with CSNPs.</p> Clinical relevance <p>Clinically, the choice between Ca(OH)<sub>2</sub> and CSNPs should be guided by treatment objectives as both medicaments give comparable bond strength, while CSNPs offer advantages for deeper and more uniform tubular penetration.</p>

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The effect of nano chitosan and calcium hydroxide intracanal medications on sealer penetration & bond strength in radicular dentin

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年5月21日

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  • Maha Nasr,
  • Ahmed El-Banna,
  • Maii Youssef Elmesellawy

摘要

Background

A three-dimensional obturation that provides a fluid tight seal of the root canal system is essential for long-term treatment success. Intracanal medicaments may hinder sealer penetration and/or affect its ability to bond with dentin. This study aimed to evaluate the sealer penetration and push-out bond strength after using Calcium hydroxide and a 2% nano-chitosan gel (CSNPs).

Methodology

Twenty-four extracted single-canal lower premolars were randomly divided, according to the intra canal medicament used, into two groups: Group A, Ca(OH)2, and Group B, 2% CSNPs. After medication placement for 1 week, all canals were sealed with gutta-percha and AH Plus sealer, mixed with 0.1% fluorescent Rhodamine B isothiocyanate. Sealer penetration was evaluated with confocal laser microscopy and then push-out bond strength was measured for both groups.

Results

For both groups, push-out bond strength varied significantly across root thirds (p < 0.001), with higher bond strength in the coronal third. The penetration radius values were significantly greater in the CSNPs group at all root levels (p ≤ 0.001). At the same time, no significant differences were found between groups or among root thirds in terms of penetration area ( p > 0.05).

Conclusions

Both Ca(OH)2 and CSNPs showed comparable push-out bond strength along the root sections, with deeper, more uniform sealer penetration with CSNPs.

Clinical relevance

Clinically, the choice between Ca(OH)2 and CSNPs should be guided by treatment objectives as both medicaments give comparable bond strength, while CSNPs offer advantages for deeper and more uniform tubular penetration.