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<p>Ureteral carcinoma, a rare malignancy typically presenting as a solitary ureteral lesion. Early diagnosis is challenging due to nonspecific clinical symptoms and subtle radiographic findings. We describe a 41-year-old male with an unusually extensive ureteral tumor that nearly occupied the full length of the right ureter. Multi-regional genomic sequencing demonstrated a branched evolutionary pattern and a complex mutational landscape.</p>

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A 41-Year-Old male with multifocal “grape-like” ureteral carcinoma involving nearly the entire ureter: a case report and management discussion

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年2月12日

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  • Yue Li,
  • Ning Liang,
  • Changming Dong,
  • Huiying Tao,
  • Tianxi Yu,
  • Shuang Wu,
  • Hao Xie,
  • Jiahao Guo,
  • Wei Lv,
  • Chunhua Lin

摘要

Ureteral carcinoma, a rare malignancy typically presenting as a solitary ureteral lesion. Early diagnosis is challenging due to nonspecific clinical symptoms and subtle radiographic findings. We describe a 41-year-old male with an unusually extensive ureteral tumor that nearly occupied the full length of the right ureter. Multi-regional genomic sequencing demonstrated a branched evolutionary pattern and a complex mutational landscape.