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Background <p>Urogenital tuberculosis (UGTB) is a rare form of extrapulmonary tuberculosis (EPTB) affecting the kidneys, ureters, and bladder. Its nonspecific symptoms often mimic common urological conditions like urinary tract infections (UTIs), leading to delayed diagnosis. This case highlights the diagnostic challenges and emphasizes the need for timely intervention to prevent irreversible renal damage.</p> Case presentation <p>A 43-year-old south-Asian female presented with sudden decreased consciousness and severe renal impairment, requiring emergency dialysis. Despite the absence of typical tuberculosis symptoms or risk factors, imaging revealed obstructive uropathy with hydronephrosis. Urine polymerase chain reaction (PCR) confirmed UGTB. Early interventions, including percutaneous nephrostomy, J-stent placement, and anti-tuberculosis therapy (ATT), resulted in significant clinical improvement.</p> Conclusions <p>UGTB should be considered in patients with unexplained urological conditions, particularly in tuberculosis-endemic regions. Early diagnosis and management are crucial to avoid irreversible complications and improve outcomes.</p>

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A rare presentation of urogenital tuberculosis leading to obstructive uropathy and renal failure: a case report

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年10月27日

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  • Abdul Qadir,
  • Nagham Sadik,
  • Mohammad Ghabashneh,
  • Husien Almarawi,
  • Mamunul Islam

摘要

Background

Urogenital tuberculosis (UGTB) is a rare form of extrapulmonary tuberculosis (EPTB) affecting the kidneys, ureters, and bladder. Its nonspecific symptoms often mimic common urological conditions like urinary tract infections (UTIs), leading to delayed diagnosis. This case highlights the diagnostic challenges and emphasizes the need for timely intervention to prevent irreversible renal damage.

Case presentation

A 43-year-old south-Asian female presented with sudden decreased consciousness and severe renal impairment, requiring emergency dialysis. Despite the absence of typical tuberculosis symptoms or risk factors, imaging revealed obstructive uropathy with hydronephrosis. Urine polymerase chain reaction (PCR) confirmed UGTB. Early interventions, including percutaneous nephrostomy, J-stent placement, and anti-tuberculosis therapy (ATT), resulted in significant clinical improvement.

Conclusions

UGTB should be considered in patients with unexplained urological conditions, particularly in tuberculosis-endemic regions. Early diagnosis and management are crucial to avoid irreversible complications and improve outcomes.