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Background <p>Deep vein thrombosis (DVT) is a common postoperative complication in patients with tibial plateau fractures. The aim of this study is to determine the incidence and risk factors of postoperative DVT in patients with tibial plateau fractures.</p> Methods <p>We conducted a retrospective study from January 1, 2023, to December 31, 2025. The primary endpoints of this study were the prone site and risk factors of DVT. Univariate analysis and multivariate Logistic regression analysis were used to analyze the related factors, and the receiver operating characteristic (ROC) curve was drawn to evaluate its predictive value.</p> Results <p>Among 890 patients, 207 (23.25%) had postoperative DVT, including 186 cases of distal thrombosis, 4 cases of proximal thrombosis, and 17 cases of mixed thrombosis, all detected DVT events were asymptomatic in the results section.Univariate analysis showed that there were significant differences in age, injury factors, fracture type, preoperative waiting time, operation time, incision length, intraoperative blood loss, preoperative hemoglobin (Hb), preoperative D-dimer, postoperative Hb, postoperative hematocrit (HCT), postoperative fibrinogen (FIB) and postoperative D-dimer levels between the two groups (<i>P</i> &lt; 0.05). Multivariate logistic regression analysis showed that preoperative and postoperative D-dimer levels were independent predictive markers of postoperative DVT in patients with tibial plateau fractures. The area under the curve (AUC) of preoperative D-dimer was 0.928(95%CI = 0.910 ~ 0.946, cut-off value: 2397.0&#xa0;ng/mL), and the AUC of postoperative D-dimer was 0.922(95%CI = 0.904 ~ 0.940, cut-off value: 2009.5&#xa0;ng/mL), and the combined prediction efficiency of the two was higher (AUC = 0.960,95%CI = 0.948 ~ 0.971).</p> Conclusion <p>Postoperative DVT in patients with tibial plateau fracture is mostly distal thrombosis. D-dimer level in the 24&#xa0;h before surgery and D-dimer level in the 24&#xa0;h after surgery are independent risk factors for postoperative DVT.</p>

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Location and risk factors of postoperative deep venous thrombosis in patients with tibial plateau fracture: a retrospective single-center study

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年5月28日

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  • Zhuo-dong Tang,
  • Ming-you Wang,
  • Hong-ping Wang,
  • Xun-zhou Song,
  • Shao-jiang Liu,
  • Yu-ping Lan,
  • Ting-yan Li

摘要

Background

Deep vein thrombosis (DVT) is a common postoperative complication in patients with tibial plateau fractures. The aim of this study is to determine the incidence and risk factors of postoperative DVT in patients with tibial plateau fractures.

Methods

We conducted a retrospective study from January 1, 2023, to December 31, 2025. The primary endpoints of this study were the prone site and risk factors of DVT. Univariate analysis and multivariate Logistic regression analysis were used to analyze the related factors, and the receiver operating characteristic (ROC) curve was drawn to evaluate its predictive value.

Results

Among 890 patients, 207 (23.25%) had postoperative DVT, including 186 cases of distal thrombosis, 4 cases of proximal thrombosis, and 17 cases of mixed thrombosis, all detected DVT events were asymptomatic in the results section.Univariate analysis showed that there were significant differences in age, injury factors, fracture type, preoperative waiting time, operation time, incision length, intraoperative blood loss, preoperative hemoglobin (Hb), preoperative D-dimer, postoperative Hb, postoperative hematocrit (HCT), postoperative fibrinogen (FIB) and postoperative D-dimer levels between the two groups (P < 0.05). Multivariate logistic regression analysis showed that preoperative and postoperative D-dimer levels were independent predictive markers of postoperative DVT in patients with tibial plateau fractures. The area under the curve (AUC) of preoperative D-dimer was 0.928(95%CI = 0.910 ~ 0.946, cut-off value: 2397.0 ng/mL), and the AUC of postoperative D-dimer was 0.922(95%CI = 0.904 ~ 0.940, cut-off value: 2009.5 ng/mL), and the combined prediction efficiency of the two was higher (AUC = 0.960,95%CI = 0.948 ~ 0.971).

Conclusion

Postoperative DVT in patients with tibial plateau fracture is mostly distal thrombosis. D-dimer level in the 24 h before surgery and D-dimer level in the 24 h after surgery are independent risk factors for postoperative DVT.