Scholarlink

Objective <p>Curved vertebroplasty (CVP), including percutaneous curved vertebroplasty (PCVP) and percutaneous curved kyphoplasty (PCKP), represents a novel surgical modality in recent years for osteoporotic vertebral compression fractures (OVCFs). Although numerous clinical studies have reported its safety and efficacy, meta-analyses remain necessary to further validate the robustness of this evidence.</p> Methods <p>Based on the PRISMA guidelines, we conducted a comprehensive literature search of four databases—PubMed, Embase, Cochrane Library, and Web of Science—for all relevant studies published from their inception to April 2025. Two investigators independently conducted a quality assessment, extracted the data, and performed all statistical analyses. In case of disagreement, a third investigator adjudicated the risk of bias assessment.</p> Results <p>A total of nine studies involving 814 patients with OVCFs were included, comprising five randomized controlled trials (RCTs) and four retrospective cohort studies (RCS). Among these, two RCTs and all RCS investigated PCVP, while the remaining three RCTs evaluated PCKP. The meta-analysis showed that compared with Percutaneous vertebral augmentation (PVA), CVP had comparable effects in terms of visual analog scale (VAS), Oswestry disability index (ODI), and improvement of the COBB angle, but significantly improved the surgical efficiency. Subgroup analysis revealed that PCVP and PCKP could consistently reduce the operation time (MD = -9.59, 95% CI: -18.93, -0.24; MD = -14.00, 95% CI: -22.40, -5.60) and the number of intraoperative fluoroscopy (MD = -5.89, 95% CI: -9.48, -2.29; MD = -26.32, 95% CI: -45.95, -6.68). However, PCVP could reduce the risk of bone cement leakage and the volume of bone cement (OR = 0.41, 95% CI: 0.24, 0.70; MD = -1.40, 95% CI: -2.29, 0.51).</p> Conclusions <p>CVP is a feasible option for treating patients with OVCFs, which could effectively enhance surgical efficiency without reducing clinical efficacy. However, its effectiveness and long-term advantages in a broader population still need to be further verified.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Efficacy and safety of curved vertebroplasty in osteoporotic vertebral compression fractures: a systematic review and meta-analysis

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年3月28日

查看全文
  • Huiyu Huang,
  • Min Yang,
  • Zhaojun Fu,
  • Lun Tan

摘要

Objective

Curved vertebroplasty (CVP), including percutaneous curved vertebroplasty (PCVP) and percutaneous curved kyphoplasty (PCKP), represents a novel surgical modality in recent years for osteoporotic vertebral compression fractures (OVCFs). Although numerous clinical studies have reported its safety and efficacy, meta-analyses remain necessary to further validate the robustness of this evidence.

Methods

Based on the PRISMA guidelines, we conducted a comprehensive literature search of four databases—PubMed, Embase, Cochrane Library, and Web of Science—for all relevant studies published from their inception to April 2025. Two investigators independently conducted a quality assessment, extracted the data, and performed all statistical analyses. In case of disagreement, a third investigator adjudicated the risk of bias assessment.

Results

A total of nine studies involving 814 patients with OVCFs were included, comprising five randomized controlled trials (RCTs) and four retrospective cohort studies (RCS). Among these, two RCTs and all RCS investigated PCVP, while the remaining three RCTs evaluated PCKP. The meta-analysis showed that compared with Percutaneous vertebral augmentation (PVA), CVP had comparable effects in terms of visual analog scale (VAS), Oswestry disability index (ODI), and improvement of the COBB angle, but significantly improved the surgical efficiency. Subgroup analysis revealed that PCVP and PCKP could consistently reduce the operation time (MD = -9.59, 95% CI: -18.93, -0.24; MD = -14.00, 95% CI: -22.40, -5.60) and the number of intraoperative fluoroscopy (MD = -5.89, 95% CI: -9.48, -2.29; MD = -26.32, 95% CI: -45.95, -6.68). However, PCVP could reduce the risk of bone cement leakage and the volume of bone cement (OR = 0.41, 95% CI: 0.24, 0.70; MD = -1.40, 95% CI: -2.29, 0.51).

Conclusions

CVP is a feasible option for treating patients with OVCFs, which could effectively enhance surgical efficiency without reducing clinical efficacy. However, its effectiveness and long-term advantages in a broader population still need to be further verified.