Scholarlink

Objectives <p>To examine the association between preoperative paraspinal muscle fat infiltration (FI) and adverse postoperative outcomes in adults with lumbar disc herniation (LDH) undergoing lumbar discectomy.</p> Methods <p>This systematic review and meta-analysis followed PRISMA. Two reviewers independently searched PubMed, Embase, Web of Science Core Collection, and the Cochrane Library. We included observational studies of adults with imaging-confirmed LDH who underwent lumbar discectomy. Eligible studies assessed preoperative paraspinal FI using magnetic resonance imaging (MRI) and reported postoperative outcomes with effect estimates. Risk of bias was assessed using the Quality In Prognosis Studies (QUIPS) tool. For dichotomous outcomes, multivariable-adjusted odds ratios (ORs) were preferentially pooled using a random-effects model.</p> Results <p>Thirteen studies including 4,371 patients were included. More severe preoperative FI was associated with a higher risk of same-level recurrence or reoperation (6 studies; pooled OR = 2.77, 95% CI 1.65–4.67; I² = 60.0%). More severe FI was also associated with residual or chronic low back pain (6 studies; pooled OR = 3.70, 95% CI 2.72–5.04; I² = 16.7%). For functional outcomes (3 studies), patients with more severe FI had worse functional scores at final follow-up (pooled mean difference = 3.856, 95% CI: 1.015–6.697; I² = 47.8%).</p> Conclusion <p>In adults with LDH undergoing lumbar discectomy, more severe preoperative paraspinal FI is associated with recurrence or reoperation, residual/chronic low back pain, and poorer functional recovery.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Preoperative paraspinal muscle fatty infiltration and prognosis after lumbar discectomy for disc herniation: a systematic review and meta-analysis

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年2月25日

查看全文
  • Hui Jin,
  • Xiangting Ye,
  • Huaiyu Ma,
  • Haoran Xu,
  • Xiaolan Liu,
  • Jingqi Zeng,
  • Fan Wang

摘要

Objectives

To examine the association between preoperative paraspinal muscle fat infiltration (FI) and adverse postoperative outcomes in adults with lumbar disc herniation (LDH) undergoing lumbar discectomy.

Methods

This systematic review and meta-analysis followed PRISMA. Two reviewers independently searched PubMed, Embase, Web of Science Core Collection, and the Cochrane Library. We included observational studies of adults with imaging-confirmed LDH who underwent lumbar discectomy. Eligible studies assessed preoperative paraspinal FI using magnetic resonance imaging (MRI) and reported postoperative outcomes with effect estimates. Risk of bias was assessed using the Quality In Prognosis Studies (QUIPS) tool. For dichotomous outcomes, multivariable-adjusted odds ratios (ORs) were preferentially pooled using a random-effects model.

Results

Thirteen studies including 4,371 patients were included. More severe preoperative FI was associated with a higher risk of same-level recurrence or reoperation (6 studies; pooled OR = 2.77, 95% CI 1.65–4.67; I² = 60.0%). More severe FI was also associated with residual or chronic low back pain (6 studies; pooled OR = 3.70, 95% CI 2.72–5.04; I² = 16.7%). For functional outcomes (3 studies), patients with more severe FI had worse functional scores at final follow-up (pooled mean difference = 3.856, 95% CI: 1.015–6.697; I² = 47.8%).

Conclusion

In adults with LDH undergoing lumbar discectomy, more severe preoperative paraspinal FI is associated with recurrence or reoperation, residual/chronic low back pain, and poorer functional recovery.