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Background <p>The European Working Group on Sarcopenia in Older People (EWGSOP2) recommends establishing population-specific cutoff points for muscle mass and function to diagnose sarcopenia globally. However, cutoff points adapted for the Brazilian population in detecting sarcopenia through physical tests remain unknown. This study aimed to evaluate the diagnostic accuracy of the Timed Up and Go (TUG) and sit-to-stand chair (5xSTS) tests in identifying sarcopenia in community-dwelling older women.</p> Methods <p>Body composition was assessed via Dual X-ray Absorptiometry, muscle strength using a Jamar dynamometer, and physical performance through the TUG and 5xSTS tests. The Sarcopenia diagnosis followed EWGSOP2 guidelines. Group comparisons were made using Mann–Whitney U test or t-test. Logistic regression was used to analyze the association between sarcopenia and performance in physical tests. The discriminatory capacity of the tests was analyzed using an ROC curve, and the cutoff points were obtained using the Youden index. Statistical significance was obtained with a p-value &lt; 0.05.</p> Results <p>Among 138 older women, 42.8% were diagnosed with sarcopenia. Women with sarcopenia were significantly older (77.1 ± 7.6 years; <i>p</i> &lt; 0.001), had lower body weight (54.8 ± 8.3&#xa0;kg; <i>p</i> &lt; 0.001), and lower body mass index (25.1 ± 4.1&#xa0;kg/m²; <i>p</i> &lt; 0.001), regarding physical performance, worse on both the TUG (14.1 ± 6.5&#xa0;s; <i>p</i> &lt; 0.001) and the 5xSTS (16.3 ± 5.6&#xa0;s; <i>p</i> = 0.02) compared to those without sarcopenia. In logistic regression analysis, higher age (OR = 1.12; 95% CI: 1.06–1.19) and slower TUG performance (OR = 1.25; 95% CI: 1.10–1.43) were associated with sarcopenia. ROC curve analysis demonstrated that only TUG test had acceptable accuracy for detecting sarcopenia (AUC = 0.703; 95% CI: 0.61–0.79; <i>p</i> &lt; 0.001), with a cutoff point of 9.8&#xa0;s.</p> Conclusion <p>These results demonstrate that cutoff points for screening or diagnosing sarcopenia using the TUG differ substantially between populations and provide an alternative that may be useful for assessing sarcopenia in community-dwelling older women.</p>

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Diagnostic accuracy of sit-to-stand chair test and timed up and go test with proposed cutoff point for identifying sarcopenia in community-dwelling older women: a cross-sectional study

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年1月8日

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  • Leonardo Augusto da Costa Teixeira,
  • Luana Aparecida Soares,
  • Maria Clara de Moura Oliveira,
  • Maria Fernanda dos Santos Mourão,
  • Liliana Pereira Lima,
  • Juliana Nogueira Pontes Nobre,
  • Henrique Silveira Costa,
  • Pedro Henrique Scheidt Figueiredo,
  • Adriana Netto Parentoni,
  • Vanessa Amaral Mendonça,
  • Ana Cristina Rodrigues Lacerda

摘要

Background

The European Working Group on Sarcopenia in Older People (EWGSOP2) recommends establishing population-specific cutoff points for muscle mass and function to diagnose sarcopenia globally. However, cutoff points adapted for the Brazilian population in detecting sarcopenia through physical tests remain unknown. This study aimed to evaluate the diagnostic accuracy of the Timed Up and Go (TUG) and sit-to-stand chair (5xSTS) tests in identifying sarcopenia in community-dwelling older women.

Methods

Body composition was assessed via Dual X-ray Absorptiometry, muscle strength using a Jamar dynamometer, and physical performance through the TUG and 5xSTS tests. The Sarcopenia diagnosis followed EWGSOP2 guidelines. Group comparisons were made using Mann–Whitney U test or t-test. Logistic regression was used to analyze the association between sarcopenia and performance in physical tests. The discriminatory capacity of the tests was analyzed using an ROC curve, and the cutoff points were obtained using the Youden index. Statistical significance was obtained with a p-value < 0.05.

Results

Among 138 older women, 42.8% were diagnosed with sarcopenia. Women with sarcopenia were significantly older (77.1 ± 7.6 years; p < 0.001), had lower body weight (54.8 ± 8.3 kg; p < 0.001), and lower body mass index (25.1 ± 4.1 kg/m²; p < 0.001), regarding physical performance, worse on both the TUG (14.1 ± 6.5 s; p < 0.001) and the 5xSTS (16.3 ± 5.6 s; p = 0.02) compared to those without sarcopenia. In logistic regression analysis, higher age (OR = 1.12; 95% CI: 1.06–1.19) and slower TUG performance (OR = 1.25; 95% CI: 1.10–1.43) were associated with sarcopenia. ROC curve analysis demonstrated that only TUG test had acceptable accuracy for detecting sarcopenia (AUC = 0.703; 95% CI: 0.61–0.79; p < 0.001), with a cutoff point of 9.8 s.

Conclusion

These results demonstrate that cutoff points for screening or diagnosing sarcopenia using the TUG differ substantially between populations and provide an alternative that may be useful for assessing sarcopenia in community-dwelling older women.